Jaknat Tofacitinib tablet is an effective solution for managing moderate-to-severe conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. This medication helps to decrease pain, tenderness, and joint swelling by mitigating inflammation. Additionally, it plays a crucial role in slowing down the advancement of bone and joint damage, offering comprehensive relief for individuals experiencing these health concerns.
Jaknat Tofacitinib tablets can be used alone or in combination with other medications. The tablets can be taken with or without food, and they should be taken at the same time every day. Your condition and the medications you are already taking will determine your dose. You should only use it in accordance with your doctor's instructions. If you stop taking this medication without consulting your doctor, your condition may worsen.
You may need to do blood tests before starting this medication. Do not start taking it if you have any infections. Consult with your doctor before starting the treatment if you have or have a history of tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Jaknat tablets may increase susceptibility to getting infections or may worsen any current infections, so precautions, such as avoiding contact with individuals with contagious illnesses like chickenpox, measles, or flu, are advisable. Under 18-year-olds should not take this medication, and your doctor may advise against using it if you are pregnant or nursing. Regular medical examinations may be necessary under your doctor's supervision.
Tofacitinib 5mg tablet uses
1. Treatment of Rheumatoid arthritis
2. Treatment of Psoriatic arthritis
3. Treatment of Ankylosing spondylitis
4. Treatment of Ulcerative colitis
5. Treatment of Alopecia
Tofacitinib tablet benefits
In the Treatment of Rheumatoid Arthritis
The mechanism of Jaknat tablets involves inhibiting certain inflammatory chemicals, leading to a reduction in joint pain, stiffness, and swelling, while also impeding the advancement of bone and joint damage. By consistently taking this medication at the same time daily, you can maximize its benefits. It is crucial to continue the treatment even if you start feeling better, as the medication not only addresses current symptoms but also serves to prevent future harm, ultimately enhancing your ability to perform daily activities and improving your overall quality of life.
In the Treatment of Psoriatic Arthritis
Psoriatic arthritis emerges in individuals with psoriasis, a condition characterized by rapid skin cell growth resulting in scales and dry patches. As a variant of inflammatory arthritis, it manifests through symptoms like joint pain, stiffness, and swelling that can fluctuate over time. Jaknat Tofacitinib tablets play a key role in alleviating the pain, stiffness, and swelling linked to this condition. Additionally, they enhance flexibility and impede disease progression, contributing significantly to the management of psoriatic arthritis and overall improvement in patients' quality of life.
In the Treatment of Ankylosing Spondylitis
Ankylosing spondylitis, a less common form of arthritis, targets the spine and larger joints, typically initiating in the lower back and potentially extending to the neck or affecting joints elsewhere. Jaknat tablets play a vital role in diminishing pain, stiffness, and swelling in the spine and joints. By enhancing flexibility and impeding the progression of the disease, these tablets contribute to a better and more active lifestyle, offering relief to individuals dealing with ankylosing spondylitis.
In the Treatment of Ulcerative Colitis
Ulcerative colitis is a condition affecting the large intestine (colon) and rectum, causing inflammation and swelling of the bowel lining. Symptoms may include bleeding, frequent diarrhea, and abdominal pain. This medication alleviates these symptoms and serves as a preventive measure against their recurrence, promoting overall well-being. It is advisable to maintain adequate hydration by consuming plenty of fluids during the course of this treatment.
How to use Tofacitinib tablet
Follow your doctor's guidance regarding the dosage and duration of this medication. Swallow the tablet whole; do not chew, crush, or break it. While Jaknat Tablet can be taken with or without food, it is recommended to take it at a consistent time for optimal results.
How Tofacitinib tablet works
Jaknat Tablet operates as a Janus kinase inhibitor, functioning by inhibiting the activity of the Janus kinase enzyme. This action leads to a reduction in immune system activity and alleviates inflammation linked to rheumatic diseases and ulcerative colitis.
Therapeutic Effects of Tofacitinib Jaknat 5mg Tablet
Tofacitinib (Jaknat) 5mg tablet comes under the category of Janus Kinase Inhibitors and functions as a disease-modifying anti-rheumatic drug (DMARD). Janus kinase, a type of tyrosine kinase enzyme, plays a role in cytokine receptor signaling. The tablet works by inhibiting Janus kinases, disrupting the transcription of genes associated with cell growth and differentiation.
Interaction of Tofacitinib (Jaknat) 5mg Tablet with other drugs
Ensure you communicate with your healthcare provider regarding all the medications you are using, encompassing prescription drugs, over-the-counter medications, vaccinations, nutritional and vitamin supplements, as well as herbal products. Some medications might interact with Tofacitinib (Jaknat) 5mg tablets, potentially diminishing their effectiveness and giving rise to undesirable side effects.
More Information about Tofacitinib 5mg Tablet
1. Store tofacitinib at room temperature (20°C to 25°C).
2. Keep the tablet out of the reach of children and pets.
3. If you forgot to take a dose, take it as soon as you remember. 4. However, if it is nearly time for the next dose, skip the missed dose.
5. Do not take a double dose to make up for a forgotten dose.
1What are the cautions of Tofacitinib (Jaknat) 5mg tablet?
If you notice any swelling in your face, lips, tongue, throat, arms, or legs, or experience difficulty swallowing or breathing, inform your doctor promptly. The use of Jaknat 5mg tablets may lead to a temporary reduction in white blood cell count, elevating the risk of infection.
2Does Jaknat 5mg tablet cause high cholesterol?Does Tofacitinib (Jaknat) 5mg tablet cause high cholesterol?
Increased cholesterol levels can result from the use of Jaknat 5mg tablets. Your doctor may check routine blood tests to monitor potential serious side effects.
3 Can Tofacitinib (Jaknat) 5mg tablet cause depression?
No, Jaknat 5mg tablets do not cause depression. Nevertheless, individuals with autoimmune conditions often experience symptoms of depression. If you are encountering signs of depression, it is advisable to promptly consult your doctor.
4Does Tofacitinib (Jaknat) 5mg tablet cause blood clots?
Yes, blood clots are reported in patients using Jaknat 5mg tablets for a longer period of time. Inform your physician if you experience any symptoms of a blood clot.
5How long does it take Tofacitinib (Jaknat) 5mg tablet to work?
Jaknat 5mg tablets are administered as a long-term treatment. Individuals who derive benefit from this course of treatment typically observe improvement within the initial 12 weeks of starting it.
6Tofacitinib citrate
The production of tofacitinib citrate involves the combination of equimolar quantities of tofacitinib and citric acid. People with moderate to severe rheumatoid arthritis are given this medicine, which works as both an antirheumatic and a non-specific protein-tyrosine kinase (EC 2.7.10.2) inhibitor. Tofacitinib is a key component of this formulation.
7Tofacitinib 5mg price in India
Tofacitinib 5mg price in India INR 1500
8Tofacitinib alopecia
Tofacitinib citrate, initially designed as a Janus kinase 1/3 inhibitor for rheumatoid arthritis, is currently repurposed for the treatment of alopecia areata. In this investigation, scientists systematically examined the medical records at the Cleveland Clinic to identify individuals with confirmed alopecia areata who underwent treatment with oral tofacitinib following a standardized regimen.
9Tofacitinib mechanism of action
Tofacitinib hinders intracellular signaling from the receptor to the cellular nucleus and suppresses inflammation through a unique pathway—specifically, the inhibition of Janus kinases—an avenue not accessible to biological medicines.
10Tofacitinib side effects
1. Black, tarry stools.
2. bladder pain.
3. bloody or cloudy urine
4. body aches or pain.
5. chest pain or tightness.
6. difficult, burning, or painful urination.
7. difficulty breathing.
8. ear congestion.
11Tofacitinib brand name
Tofacitinib, sold under the brand name Xeljanz among others like Tofajak, Jakura, Jaknat, T Jaki, etc,
12Tofacitinib vitiligo
Vitiligo is a skin disorder of autoimmune origin characterized by depigmented areas on the skin.
13Topical tofacitinib
Vitiligo is an autoimmune skin condition leading to depigmented skin areas. Recent research suggests that Janus kinase (JAK) inhibitors could be a viable treatment. Our case study involves an adolescent patient with an extensive and resistant history of vitiligo. After using a JAK inhibitor called tofacitinib on the skin for 9 months and phototherapy, there was a lot of repigmentation, which shows that the treatment worked.
14Tofacitinib 5mg price
Tofacitinib 5mg price: INR 313
15Tofacitinib 5 mg price
Tofacitinib 5 mg price: INR 313
16Tofacitinib 5mg price in india
Tofacitinib 5mg price in india: INR 313
17Tofacitinib 5 mg price in india
Tofacitinib 5 mg price in india: INR 313
18Tofacitinib 5mg tablet price
Tofacitinib 5mg tablet price: INR 313
19Tofacitinib 5 mg tablet price
Tofacitinib 5 mg tablet price: INR 313
20Jaknat 5mg price
Jaknat 5mg price: INR 313
21Jaknat 5 mg price
Jaknat 5 mg price: INR 313
22Jaknat 5 mg price in india
Jaknat 5 mg price in india: INR 313
23Jaknat 5mg price in india
Jaknat 5mg price in india: INR 313
24Tofacitinib 5mg tablet
Tofacitinib 5mg tablet
Tofacitinib is used, either alone or in combination with other medications, to treat rheumatoid arthritis in adults. This condition, where the body attacks its own joints, leads to pain, swelling, and loss of function. Tofacitinib is prescribed for patients who cannot take or did not respond to one or more tumor necrosis factor (TNF) inhibitors.
