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Palbociclib 125mg Capsules (Piclib)
Original price was: $114.00.$67.50Current price is: $67.50.
United States dollar
Salt Composition: Palbociclib
Manufacturer: Hetero Healthcare
Packaging Size: 21 Capsules
Delivery Services
Palbociclib 125mg Capsules (Piclib) - Uses, Benefits, Price in India, Side Effects
Palbociclib 125mg Capsules (Piclib) is used to treat certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) that have spread to other organs. It is administered in conjunction with hormonal anti-cancer therapies.
Palbociclib 125mg Capsule should be consumed with food, ideally at the same time, daily, to maximize their benefits. Your physician will determine the appropriate dosage and frequency based on your condition, which may vary over time. It's essential to adhere to your doctor's instructions precisely. Misuse or overconsumption can lead to severe side effects. Although it might take weeks or even months to see the benefits, don't stop using it unless your doctor tells you to.
Prior to taking this medication, inform your doctor if you have a history of heart disease, liver or kidney issues, or if you are currently using medications to treat infections. Informing your healthcare provider about all your medications is crucial, as this medication can interact with or influence many other drugs. Avoid using this medicine during pregnancy or while breastfeeding. We recommend effective contraception for both males and females during treatment to prevent pregnancy.
Palbociclib 125mg Capsule should be consumed with food, ideally at the same time, daily, to maximize their benefits. Your physician will determine the appropriate dosage and frequency based on your condition, which may vary over time. It's essential to adhere to your doctor's instructions precisely. Misuse or overconsumption can lead to severe side effects. Although it might take weeks or even months to see the benefits, don't stop using it unless your doctor tells you to.
Prior to taking this medication, inform your doctor if you have a history of heart disease, liver or kidney issues, or if you are currently using medications to treat infections. Informing your healthcare provider about all your medications is crucial, as this medication can interact with or influence many other drugs. Avoid using this medicine during pregnancy or while breastfeeding. We recommend effective contraception for both males and females during treatment to prevent pregnancy.
Palbociclib 125 mg capsule uses in Breast Cancer
Palbociclib 125mg Capsule Benefits
Breast Cancer
Palbociclib 125mg Capsule is effective in treating breast cancer and can be utilized alone or in conjunction with other medications or treatment methods, such as chemotherapy. It alleviates breast cancer symptoms such as breast lumps, bloody discharge from nipples, or alterations in breast shape or texture. Palbociclib capsules halt cancer cell growth and inhibit multiplication. If any side effects are troublesome, consult your doctor for guidance.How Palbociclib 125 mg capsule works
Palbociclib 125mg Capsule is an anti-cancer medication that operates by targeting cyclin-dependent kinases 4 and 6, which are chemical messengers downstream of signaling pathways that drive cell proliferation. By inhibiting cyclin-dependent kinases 4 and 6, this medicine halts the cancer cell cycle, effectively impeding cell growth. Additionally, it specifically targets estrogen receptor-positive breast cancer cells by disrupting the cell cycle.
How to use Palbociclib 125 mg capsule
Follow your doctor's instructions regarding the dosage and duration of
Palbociclib 125mg capsules. It should be taken with food.
Therapeutic Effects of Piclib Palbociclib 125 mg Capsule
Piclib 125mg Capsule functions by inhibiting the activity of cyclin-dependent kinases 4 and 6, essential for cell division and growth. This action slows cell growth and impedes the spread of cancer cells.
Interaction of Palbociclib 125 mg capsule with other drugs
Before starting treatment, discuss with your doctor all your medications, whether prescribed, over-the-counter, nutritional, or vitamin supplements, as well as any herbal products you have previously taken. It's essential to note that concurrent use of
Palbociclib 125mg capsule with CYP3A4 inhibitors like fentanyl has been associated with increased fentanyl toxicity. Some medications may interact with the drug's efficacy.
Palbociclib 125mg Capsule Price in India
Palbociclib 125mg Capsules are available in India at competitive prices. The cost may vary depending on the manufacturer (Pfizer, Natco, Hetero, Aprazer, Cipla, etc), packaging size, and distributor margins. Export prices differ from domestic supply, and GMP certification ensures compliance for international buyers.
How Palbociclib 125mg Capsule Works (Mechanism of Action)
Palbociclib works like a brake on cancer cells. It blocks the proteins that tell cancer cells to keep dividing. When combined with hormone therapy, it helps control HR‑positive, HER2‑negative breast cancer more effectively and delays disease progression.
Sources:
DrugBank: Palbociclib mechanism of action (CDK4/6 inhibitor)
BC Cancer Monograph: Palbociclib blocks transition from G1 to S phase by inhibiting Rb phosphorylation.
Sources:
More Information about Palbociclib Capsule
Fact Box of Palbociclib capsule
References
FAQ - Palbociclib
1Is Palbociclib 125 mg capsule a form of targeted therapy?
Yes, Palbociclib 125mg capsule is categorized as targeted therapy and is classified as a cyclin-dependent kinase inhibitor.
2Is hair loss a common side effect of the Palbociclib 125 mg capsule?
Certainly, hair loss or thinning is a potential side effect of taking Palbociclib 125mg capsule may cause hair loss or thinning. If you experience any side effects, including this one, consult your doctor for guidance.
3Is Palbociclib 125 mg capsule suitable for use in children?
Palbociclib 125mg capsule is not recommended for adolescents or children under 18 years old.
4Can Palbociclib 125 mg capsule impact fertility?
Yes, Palbociclib 125mg capsule may potentially diminish fertility in men, impacting their ability to father children. Therefore, it is advisable for men to contemplate sperm preservation prior to initiating this medication.
5Can Palbociclib 125 mg capsule affect blood cell count?
Rewriting this Palbociclib 125mg capsule may decrease the count of white blood cells, potentially weakening the immune system and increasing susceptibility to infections. Regular blood tests are recommended during the Palbociclib (Piclib) 125mg capsule treatment.
6Palbociclib
Palbociclib
Palbociclib is prescribed alongside another medication as an initial therapy for a specific type of hormone receptor-positive, advanced breast cancer that has metastasized. Additionally, it is used with fulvestrant (Faslodex) to treat hormone receptor-positive, advanced breast cancer in individuals who have previously responded to antiestrogen treatment like tamoxifen (Soltamox). Palbociclib, a kinase inhibitor, works by inhibiting the abnormal protein activity that causes cancer cells to proliferate, thereby impeding or slowing cancer cell spread.7abemaciclib palbociclib ribociclib
abemaciclib palbociclib ribociclib
When compared to palbociclib, ribociclib exhibited notably higher gastrointestinal (GI) toxicity, including an increased incidence of grade 1–2 nausea, grade 1–2 vomiting, grade 3–4 vomiting, and grade 3–4 transaminitis. Conversely, abemaciclib demonstrated significantly more diarrhea of any grade and a higher incidence of grade 3–4 anemia compared to ribociclib.8palbociclib brand name
palbociclib brand name
1. Piclib2. Ciclib 125mg
3. Bdpalbo 125mg
4. Palnat 125mg
5. Pabreca 125mg
6. Kixta 125mg
9palbociclib package insert
palbociclib package insert
palbociclib package insert film coated capsule10palbociclib side effects
palbociclib side effects
1. Tiredness2. Hair loss
3. Dry skin, rash
4. Infections
5. Low blood cell counts
6. Decreased of appetite
7. Nausea, vomiting
8. Diarrhea
9. Swelling of lips and mouth
10. Changes in taste
11. Nose bleed
12. Dry eye, blurred vision, increased
13. tearing
11palbociclib mechanism of action
palbociclib mechanism of action
In cancer cells that have a functional retinoblastoma tumor suppressor gene (RB), palbociclib stops cell growth and DNA replication because of how it works.12palbociclib cost
palbociclib cost
Palbociclib cost: INR 310013 palbociclib prescribing information
palbociclib prescribing information
Follow your doctor's instructions regarding the dosage and duration of Palbociclib (Piclib) capsules. It should be taken with food.14palbociclib price
palbociclib price
: INR 310015side effects of palbociclib
side effects of palbociclib
1. Tiredness2. Hair loss
3. Dry skin, rash
4. Infections
5. Low blood cell counts
6. Decreased of appetite
7. Nausea, vomiting
8. Diarrhea
9. Swelling of lips and mouth
10. Changes in taste
11. Nose bleed
12. Dry eye, blurred vision, increased tearing
16palbociclib 125mg price in India
palbociclib 125mg price in India
: INR 310017palbociclib 125 mg price
palbociclib 125 mg price
: INR 310018palbociclib 125mg capsule
palbociclib 125mg capsule
Palbociclib is a type of medication known as a kinase inhibitor. It functions by blocking the abnormal protein that signals cancer cells to multiply, helping to slow down or stop their spread.19What is the price of Palbociclib 125mg capsule in India?
The price of Palbociclib 125mg capsules in India varies depending on the brand and supplier. We offer competitive wholesale rates and export options. Contact us for the latest pricing.
20Can I buy Palbociclib capsules online?
Yes, you can buy Palbociclib capsules online through verified pharmaceutical distributors in India. We provide secure packaging and worldwide shipping for bulk and individual orders.
21What are the uses of Palbociclib capsules in breast cancer?
Palbociclib is used to treat HR-positive, HER2-negative advanced or metastatic breast cancer, often in combination with hormone therapy like letrozole or fulvestrant.
22What are the side effects of Palbociclib 125mg capsules?
Common side effects include fatigue, nausea, decreased white blood cell count, and infections. Patients should be monitored regularly by their doctor during treatment.
23Do you supply Palbociclib 125mg Capsules in bulk for export?
Yes, Palbociclib 125mg Capsules are available for bulk export orders with GMP certification, proper documentation, and reliable logistics support.
24What is the price of Palbociclib 125mg Capsules in India?
Prices vary depending on manufacturer and pack size. Competitive quotations are provided for domestic buyers and export clients.
25What is the HS code for Palbociclib 125mg Capsules?
The HS code commonly used is 30049099, applicable for customs clearance and international trade documentation.
26Are Indian suppliers reliable for Palbociclib 125mg Capsules exports?
Yes, India is a trusted supplier of oncology medicines, offering Palbociclib 125mg Capsules with compliance to global quality standards.
27Do you provide worldwide shipping for Palbociclib 125mg Capsules?
Yes, we ship Palbociclib 125mg Capsules globally with customs clearance support and timely delivery to major export destinations.
All Substitutes
Palbociclib brands in india
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Ciclib 125mg capsule | 21 capsule | Shilpa Medicare | INR 2700 |
| Bdpalbo 125mg capsule | 21 capsule | BDR Pharmaceuticals | INR 3200 |
| Palnat 125mg capsule | 21 capsule | Natco Pharma | INR 2980 |
| Palbocib 125mg capsule | 21 capsule | Aprazer Healthcare | INR 4000 |
| Kixta 125mg capsule | 21 capsule | Zydus Cadila | INR 3550 |
| Piciclib 125mg capsule | 21 capsule | Cipla Ltd | INR 4050 |
| Palbace 125mg capsule | 21 capsule | Pfizer Ltd | INR 17900 |
Side Effects
Palbociclib side effects
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
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