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Pomalidomide 4mg Capsules (Pomcad)
Original price was: $119.93.$88.50Current price is: $88.50.
United States dollar
Salt Composition: Pomalidomide
Manufacturer: Cadila Pharmaceuticals
Packaging Size: 21 Capsules
Delivery Services
Pomalidomide Capsules 4 Mg (Pomcad) – Overview & Benefits
Pomalidomide capsules 4 Mg (Pomcad) are used in patients with multiple myeloma, especially when combined with another medication (dexamethasone). Their mechanism involves assisting the bone marrow in generating healthy blood cells and eliminating irregular cells.
Pomalidomide 4mg capsules can be taken with or without food, but it's best to stick to a regular daily schedule. Your physician will determine the appropriate dosage and frequency based on your specific condition, which may be subject to adjustments over time. It is crucial to follow your doctor's instructions precisely, as improper usage or exceeding the prescribed dose may lead to severe side effects. While it might take several weeks or months to observe the therapeutic effects, refrain from discontinuing the medication unless directed to do so by your doctor.
This medication may interact with or have an impact on a variety of other medications; let your medical team know about all the medications you are currently taking. Avoid using this medication during pregnancy or while breastfeeding. To prevent pregnancy, both males and females should use effective contraception during the course of treatment. Exercise caution when exposed to sunlight, as this medicine can increase skin sensitivity. Consider wearing protective clothing when outdoors.
Pomalidomide 4mg capsules can be taken with or without food, but it's best to stick to a regular daily schedule. Your physician will determine the appropriate dosage and frequency based on your specific condition, which may be subject to adjustments over time. It is crucial to follow your doctor's instructions precisely, as improper usage or exceeding the prescribed dose may lead to severe side effects. While it might take several weeks or months to observe the therapeutic effects, refrain from discontinuing the medication unless directed to do so by your doctor.
This medication may interact with or have an impact on a variety of other medications; let your medical team know about all the medications you are currently taking. Avoid using this medication during pregnancy or while breastfeeding. To prevent pregnancy, both males and females should use effective contraception during the course of treatment. Exercise caution when exposed to sunlight, as this medicine can increase skin sensitivity. Consider wearing protective clothing when outdoors.
Pomalidomide 4 mg capsule uses
Pomalidomide 4mg Capsule is mainly used to treat:
1. Multiple Myeloma – a type of blood cancer that affects the bone marrow.
2. Kaposi’s Sarcoma – a rare type of cancer that causes patches of abnormal tissue to grow under the skin or in the mouth. It is usually given when other treatments have not worked well. Pomalidomide helps slow down or stop the growth of cancer cells and boosts the immune system to fight the disease.
1. Multiple Myeloma – a type of blood cancer that affects the bone marrow.
2. Kaposi’s Sarcoma – a rare type of cancer that causes patches of abnormal tissue to grow under the skin or in the mouth. It is usually given when other treatments have not worked well. Pomalidomide helps slow down or stop the growth of cancer cells and boosts the immune system to fight the disease.
Pomalidomide 4 mg capsule benefits
Benefits of Pomalidomide 4mg Capsules:
1. Effective in Resistant Multiple Myeloma2. Boosts the Immune System
3. Inhibits Tumor Growth
4. Oral Therapy
5. Works in Combination Therapy
Potential Use in Kaposi’s Sarcoma
How to use Pomalidomide 4 mg capsule
General Instructions for Use:
1. Take as prescribed by your doctor
Usual dose: Once daily.
Take it at the same time every day, preferably in the evening or as advised.
2. Take with or without food
It can be taken on an empty stomach or with food, depending on how it suits your stomach.
3. Swallow whole
Do not break, crush, or chew the capsule.
Swallow with a full glass of water.
4. Use gloves if handling opened capsules
Pomalidomide is hazardous if the powder is touched or inhaled, especially by pregnant women.
5. Duration of treatment
Usually given in cycles (e.g., 21 days on medicine, 7 days off), but follow your doctor’s exact schedule.
Precautions:
Pregnancy warning:
Do not use if you are pregnant or planning pregnancy. It's highly teratogenic (can harm the baby).
Contraception:
Both men and women must use reliable birth control before, during, and after treatment (at least 4 weeks after).
Blood tests:
Regular CBC, liver function, and kidney function tests are required during treatment.
Missed Dose:If you miss a dose by less than 12 hours, take it as soon as you remember.
If more than 12 hours have passed, skip the missed dose and continue the regular schedule.
Do not take two doses at the same time.
Storage:
Keep in original packaging.
Store at room temperature, away from heat and moisture.
Keep out of reach of children and pregnant women.
1. Take as prescribed by your doctor
Precautions:
Missed Dose:
Storage:
How Pomalidomide 4 mg capsule works
How Pomalidomide 4mg Capsule Works:
1. Boosts the Immune System
It activates immune cells like T cells and natural killer (NK) cells.
These activated immune cells then attack and kill cancer cells.
2. Inhibits Blood Supply to Tumor (Anti-angiogenesis)
It blocks the formation of new blood vessels (angiogenesis) that tumors need to grow.
Without a blood supply, the tumor can’t get oxygen and nutrients.
3. Direct Anti-Cancer EffectIt interferes with the cancer cells' internal functions, leading to their death (apoptosis).
Also blocks the signals that cancer cells use to grow and survive.
4. Modifies the MicroenvironmentPomalidomide disrupts the protective environment around cancer cells in the bone marrow, making them more vulnerable to destruction.
1. Boosts the Immune System
2. Inhibits Blood Supply to Tumor (Anti-angiogenesis)
3. Direct Anti-Cancer Effect
4. Modifies the Microenvironment
Therapeutic Effects of Pomcad Pomalidomide 4 mg Capsules
Pomcad 4mg capsules work by making it easier for the immune system to target cancer cells, stopping the growth of blood vessels that bring nutrients to the cancer cells, and stopping the growth of cancer cells, especially myeloma cells.
Interaction of Pomalidomide 4 mg Capsule with other drugs
Pomalidomide 4mg capsule can interact with several other drugs, which may increase the risk of side effects or reduce its effectiveness. Below is a categorized list of important drug interactions you should be aware of:
Medicines to Be Careful With:
1. Some antibiotics (like Ciprofloxacin)They can increase the power of Pomalidomide and cause more side effects.
2. Medicines for seizures (like Phenytoin, Carbamazepine)
These can reduce the effect of Pomalidomide, making it less useful.
3. Blood thinners (like Warfarin, Apixaban)
Taking them together can increase the risk of bleeding or bruising.
4. Other cancer medicines (like Lenalidomide, Dexamethasone)
When used together, they may cause more weakness in your blood (low counts) and increase clot risk, but sometimes doctors give them together carefully.
5. Birth control pills (with estrogen)
Can increase the chance of blood clots. It’s better to use non-hormonal birth control (like copper IUD or condoms).
Things That Can Make Side Effects Worse:
Sleeping pills, alcohol, or anxiety medicines
➤ These can make you feel more sleepy or dizzy.
Live vaccines (like MMR, BCG)
➤ Don't take them while on Pomalidomide – your body might not fight the infection properly.
Medicines That Are Safe to Take:
Paracetamol (for fever or pain)
Most antibiotics (except some like Rifampin)
Antacids (just take them 2 hours before or after Pomalidomide)
Avoid Grapefruit Juice
It can change how your body handles the medicine.
Tip:
Always tell your doctor or pharmacist about all medicines you take, including:
Home remedies
Supplements
Ayurvedic or herbal products
Medicines to Be Careful With:
1. Some antibiotics (like Ciprofloxacin)
Things That Can Make Side Effects Worse:
Medicines That Are Safe to Take:
Avoid Grapefruit Juice
Tip:
Always tell your doctor or pharmacist about all medicines you take, including:
Piece of Advice
We recommend using effective birth control for at least 4 weeks before initiating treatment, throughout the treatment period, and for at least 4 weeks after concluding pomalidomide capsule treatment. Pregnant women or those suspecting pregnancy should avoid using this medication. To prevent skin contact, handle this medication with disposable gloves. Do not share Pomalidomide 4mg capsules with others, even if they show similar symptoms, as it may lead to birth defects and other severe issues. Avoid donating blood or sperm during treatment and for seven days after the drug's completion.
References
FAQ - Pomalidomide
1What class of medication is Pomalidomide 4 mg Capsule?
Pomalidomide 4mg Capsule belongs to the class of medications called:
Immunomodulatory agents (IMiDs)
Specifically, it is a thalidomide analog.
Immunomodulatory agents (IMiDs)
Specifically, it is a thalidomide analog.
2What is the best time to take Pomalidomide 4 mg Capsule?
Best Time to Take Pomalidomide 4mg Capsule:
Take it at the same time every day, preferably at night or in the evening — unless your doctor advises otherwise.
It can be taken with or without food.
3Can children use Pomalidomide 4 mg Capsule?
No, Pomalidomide 4mg Capsule is not recommended for use in children.
Why not:
Safety and effectiveness in children have not been established through clinical studies.
It is mainly used to treat multiple myeloma, a cancer that typically occurs in adults.
Special caution:
It can cause serious side effects, including harm to unborn babies (birth defects), severe blood problems, and infections — so it is strictly regulated.
Pomalidomide is for adult use only and should not be given to children unless a specialist doctor has made an exceptional case and is closely monitoring treatment.
Why not:
4Can I donate blood during Pomalidomide 4 mg Capsule treatment?
No, you should NOT donate blood during treatment with Pomalidomide 4mg Capsule.
Why you should avoid blood donation:
1. Risk of birth defects:
If your donated blood is given to a pregnant woman, it could cause severe birth defects or death of the unborn baby, even if the pregnant woman is not directly taking the medicine.
2. Strict safety rules:
Pomalidomide is closely related to thalidomide, a drug known to cause serious birth defects. Because of this, its use is tightly controlled under special pregnancy prevention programs.
When can you donate blood again?
You can donate blood at least 1 month after stopping pomalidomide treatment — but only after getting clearance from your doctor.
Summary:
❗ Do not donate blood during and for 1 month after treatment with Pomalidomide. This rule applies to all patients, including males.
Why you should avoid blood donation:
1. Risk of birth defects:
If your donated blood is given to a pregnant woman, it could cause severe birth defects or death of the unborn baby, even if the pregnant woman is not directly taking the medicine.
2. Strict safety rules:
Pomalidomide is closely related to thalidomide, a drug known to cause serious birth defects. Because of this, its use is tightly controlled under special pregnancy prevention programs.
When can you donate blood again?
❗ Do not donate blood during and for 1 month after treatment with Pomalidomide. This rule applies to all patients, including males.
5In which conditions should I avoid taking Pomalidomide 4 mg Capsule?
You should avoid taking Pomalidomide 4mg Capsule in the following conditions unless your doctor has clearly advised otherwise:
1. Pregnancy
Strictly prohibited – it can cause severe birth defects or death of the unborn baby.
Even one capsule can be harmful during pregnancy.
Women of childbearing age must use 2 reliable methods of contraception before, during, and after treatment (for at least 4 weeks after stopping).
2. Breastfeeding
Avoid use – it is unknown if the medicine passes into breast milk, but it may harm the baby.
3. Allergy to Pomalidomide or similar drugs
Do not take it if you have had an allergic reaction (rash, itching, breathing trouble) to pomalidomide, thalidomide, or lenalidomide in the past.
4. Severe liver or kidney disease
Pomalidomide is processed in the liver and kidneys. If you have severe liver or kidney problems, it may build up in your body and increase side effects.
5. Low white blood cell or platelet counts
It can further lower your blood counts, increasing the risk of infections or bleeding.
Your doctor may check your CBC before and during treatment.
6. Active serious infections
Avoid starting treatment if you have an uncontrolled or severe infection.
7. Blood clot history
If you've had deep vein thrombosis (DVT) or pulmonary embolism (PE), discuss it with your doctor. Pomalidomide increases the risk of clotting.
Always inform your doctor about:
Any heart conditions, other medications, or herbal products you’re using.
Any recent surgery, or if you're planned for any dental/medical procedures.
1. Pregnancy
6Can I share Pomalidomide 4 mg Capsule with other people?
No, you should never share Pomalidomide 4mg Capsule with anyone.
Why it is dangerous to share:
1. Risk of birth defects:
Even one dose can cause severe, life-threatening birth defects if taken by a pregnant woman or someone who becomes pregnant.
2. Strict safety regulations:
Pomalidomide is distributed under special safety programs due to its high risk. Only those who are properly screened and monitored by doctors should take it.
3. Serious side effects:
It can cause low blood counts, infections, blood clots, and liver problems.
Without proper medical supervision and lab tests, it can be very harmful to others.
4. Individual dosing:
The dosage and duration vary based on the patient’s condition, age, blood reports, and other medications.
What’s safe for you may be dangerous for someone else.
Summary:
❗ Never share Pomalidomide with anyone, even if they have similar symptoms. It should only be used by the person it was prescribed for, under strict medical supervision.
Why it is dangerous to share:
1. Risk of birth defects:
❗ Never share Pomalidomide with anyone, even if they have similar symptoms. It should only be used by the person it was prescribed for, under strict medical supervision.
7What should I do if I miss my Pomalidomide 4 mg Capsule dose?
💊 What to Do If You Miss a Dose of Pomalidomide 4mg Capsule:
It depends on how much time has passed since the missed dose:
If LESS than 12 hours since your usual dose time:
Take the missed dose as soon as you remember.
If MORE than 12 hours since your usual dose time:
❌ Skip the missed dose.
✅ Take your next dose at the regular time the next day.
❗ Do not double the dose to make up for the missed one — this can lead to serious side effects.
📌 Helpful Tips:
Try to take your capsule at the same time every day to reduce the chance of missing it.
Set a daily alarm or reminder if needed.
🚨 If you miss multiple doses:
Contact your doctor before restarting — they may need to adjust your treatment or do blood tests first.
It depends on how much time has passed since the missed dose:
If LESS than 12 hours since your usual dose time:
8 I am suffering from a Hepatitis B virus infection. Can I take Pomalidomide 4 mg Capsule?
If you have Hepatitis B virus (HBV) infection, you must inform your doctor before taking Pomalidomide 4mg Capsule. Here's why:
⚠️ Caution: Pomalidomide and Hepatitis B
Pomalidomide can weaken your immune system, which may cause reactivation of hepatitis B — even if your infection is inactive or under control.
This reactivation can lead to serious liver damage, and in some cases, it may be life-threatening.
🩺 What you should do:
1. Tell your doctor about your hepatitis B history before starting Pomalidomide.
2. Your doctor may:Order HBV DNA tests or liver function tests (LFTs)
Start you on antiviral medicine to prevent reactivation.
Start you on antiviral medicine to prevent reactivation.
Monitor your liver closely during treatment.
✅ Can you take it?
Possibly yes, but only under close medical supervision with hepatitis B monitoring and antiviral protection.
⚠️ Caution: Pomalidomide and Hepatitis B
1. Tell your doctor about your hepatitis B history before starting Pomalidomide.
2. Your doctor may:
Possibly yes, but only under close medical supervision with hepatitis B monitoring and antiviral protection.
9Pomalidomide moa
Pomalidomide moa
🧬 Mechanism of Action (MOA) of Pomalidomide:Pomalidomide works through multiple mechanisms to fight multiple myeloma and other cancers. Here's a simple explanation:
1. Immune System Activation
Pomalidomide kills cancer cells by activating the immune system, stopping new blood vessels, and destroying proteins that cancer cells need to survive.
10Pomalidomide brand name
Pomalidomide brand name
11Pomalidomide mechanism of action
Pomalidomide mechanism of action
🧬 Mechanism of Action (MOA) of Pomalidomide:Pomalidomide works through multiple mechanisms to fight multiple myeloma and other cancers. Here's a simple explanation:
1. Immune System Activation
Pomalidomide kills cancer cells by activating the immune system, stopping new blood vessels, and destroying proteins that cancer cells need to survive.
12What is Pomalidomide 4mg used for?
Pomalidomide 4mg is used in the treatment of multiple myeloma, a type of blood cancer. It is typically prescribed in combination with other medications like dexamethasone for patients who have not responded to prior therapies.
13How should I take Pomalidomide 4mg capsules?
Pomalidomide 4mg should be taken exactly as prescribed by your doctor, usually once daily on specific days of a 28-day cycle. Swallow the capsule whole with water, without opening or crushing it, and take it on an empty stomach or as directed.
14What are the side effects of Pomalidomide 4mg?
Common side effects include fatigue, nausea, constipation, low white blood cell count (neutropenia), and increased risk of infections. Serious side effects may include blood clots or severe allergic reactions. Always consult your doctor if you experience unusual symptoms.
15Is Pomalidomide 4mg safe during pregnancy?
No, Pomalidomide 4mg is highly teratogenic and can cause severe birth defects or fetal death. It is strictly contraindicated in pregnancy. Women of childbearing age must use two reliable forms of contraception and undergo regular pregnancy tests during treatment.
16Can I buy Pomalidomide 4mg online with a prescription?
Yes, Pomalidomide 4mg can be purchased online from licensed pharmacies with a valid prescription. Ensure that the pharmacy follows regulatory guidelines for dispensing this restricted medication, as special safety programs are often required.
17What are Pomalidomide 4mg Capsules used for?
Pomalidomide 4mg Capsules are prescribed for the treatment of multiple myeloma, usually in combination with dexamethasone. They belong to the class of immunomodulatory agents that help bone marrow produce normal blood cells and target abnormal cells.
18Do you supply Pomalidomide 4mg Capsules for export?
Yes, Pomalidomide 4mg Capsules are available for bulk export with GMP certification, proper documentation, and worldwide shipping support. Compliance with international trade regulations is ensured.
19What is the HS code for Pomalidomide 4mg Capsules?
The commonly used HS code is 30049099, applicable for customs clearance and international trade documentation of Pomalidomide 4mg Capsules.
20Are there safety warnings for Pomalidomide 4mg Capsules?
Yes. Pomalidomide carries a boxed warning for embryo‑fetal toxicity and risk of blood clots. It is contraindicated in pregnancy and available only through restricted programs like POMALYST REMS® in the U.S..
All Substitutes
Pomalidomide brands in india
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Pomide 4mg capsule | 21 Capsules | Hetero Healthcare | INR 4900 |
| Bdpoma 4mg capsule | 21 Capsules | BDR Pharmaceuticals | INR 5200 |
| Pomavia 4mg capsule | 21 Capsules | Lupin Ltd | INR 9200 |
| Pomalid 4mg capsule | 21 Capsules | Natco Pharma | INR 7800 |
Side Effects
Pomalidomide capsule side effects
- Fatigue
- Fever
- Bone pain
- Muscle cramp
- Diarrhea
- Nausea
- Constipation
- Breathing problems
- Cough
- Decreased appetite
- Decreased white blood cell count (neutrophils)
- Low blood platelets
- Decreased white blood cell count (lymphocytes)
- Anemia (a low number of red blood cells)
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