Everolimus 5mg Tablet (Afinitor)
$161.55 Original price was: $161.55.$150.00Current price is: $150.00.
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Salt Composition: Everolimus
Manufacturer: Novartis India
Packaging Size: 10 Tablet
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Everolimus 5mg Tablet (Afinitor) – Overview & Benefits
Everolimus 5mg Tablet (Afinitor) helps prevent the body from rejecting a transplanted organ by controlling the immune system so it can accept the new organ. It is also used along with other medicines to treat cancers of the breast, pancreas, lungs, and kidneys.
Take everolimus 5 mg tablets exactly as your doctor prescribes, in the correct dose and for the right duration. You can take it with or without food, but try to take it at the same time each day. Do not take more than the recommended dose, as an overdose can cause serious side effects.
Before starting this medicine, talk to your doctor if you're taking any other medications or have any existing health conditions. If you are pregnant or breastfeeding, let your doctor know before beginning treatment. During the course of treatment, your doctor may ask for some lab tests to check how the medicine is affecting your body. This medicine may impact fertility in both men and women, so speak to your doctor if you are planning to have a child.
Take everolimus 5 mg tablets exactly as your doctor prescribes, in the correct dose and for the right duration. You can take it with or without food, but try to take it at the same time each day. Do not take more than the recommended dose, as an overdose can cause serious side effects.
Before starting this medicine, talk to your doctor if you're taking any other medications or have any existing health conditions. If you are pregnant or breastfeeding, let your doctor know before beginning treatment. During the course of treatment, your doctor may ask for some lab tests to check how the medicine is affecting your body. This medicine may impact fertility in both men and women, so speak to your doctor if you are planning to have a child.
Uses of Everolimus 5mg tablet
1. Organ Transplant:
Prevents rejection of kidney or liver transplants by suppressing the immune system.
2. Cancer Treatment:
Breast Cancer: Used for advanced hormone receptor-positive, HER2-negative breast cancer.
Kidney Cancer: Treats advanced renal cell carcinoma when other treatments fail.
Pancreatic Neuroendocrine Tumors: Helps control tumor growth in the pancreas.
Lung Neuroendocrine Tumors: Used for treating certain slow-growing lung tumors.
Brain Tumors: Manages subependymal giant cell astrocytoma (SEGA), especially in patients with tuberous sclerosis complex (TSC).
Renal Angiomyolipoma: Treats non-cancerous kidney tumors associated with TSC.
Benefits of Everolimus 5mg Tablet
How Everolimus 5mg tablet works
Everolimus 5 mg tablet works by targeting and blocking a protein called mTOR (mammalian target of rapamycin). Here's how it functions:
1. Immune System Regulation (for organ transplant patients):mTOR is involved in the immune system’s response. By inhibiting mTOR, Everolimus reduces the activity of the immune system, preventing it from rejecting a transplanted organ (like a kidney or liver).
2. Cancer Treatment:
mTOR helps cancer cells grow and divide. By blocking this protein, Everolimus slows down or stops the growth of cancer cells, especially in tumors of the breast, pancreas, kidneys, lungs, and brain.
In simple terms, Everolimus helps prevent organ rejection by calming the immune system and fights cancer by slowing down the growth of abnormal cells.
1. Immune System Regulation (for organ transplant patients):
How to use Everolimus 5mg tablet
1. Follow Your Doctor's Instructions:
Always take Everolimus tablet exactly as your doctor prescribes. The dosage and duration will depend on your specific condition.
2. When to Take:
Take the tablet at the same time each day to help you remember.
You can take it with or without food.
3. Swallow the Tablet Whole:
Do not crush, chew, or break the tablet. Swallow it whole with a glass of water.
4. Avoid Overdose:
Do not take more than the prescribed dose. An overdose may cause serious side effects.
If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose. Do not take two doses at once.
5. Regular Check-ups:
Your doctor may recommend regular blood tests to check how the medicine is affecting your body.
6. Other Instructions:
If you’re pregnant, breastfeeding, or planning to have a child, consult your doctor before using Everolimus.
Always take Everolimus tablet exactly as your doctor prescribes. The dosage and duration will depend on your specific condition.
2. When to Take:
Therapeutic Effects of Afinitor Everolimus 5mg tablet
Afinitor 5mg tablet works by blocking a protein called mTOR (mammalian target of rapamycin), which controls cell growth. By inhibiting mTOR, everolimus slows the growth of abnormal cancer cells, reduces tumor size, and can improve outcomes in patients with certain cancers.
Interaction of Everolimus 5mg tablte with other drugs
Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medicines, vitamin or nutritional supplements, and herbal products. Some medications may interact with the everolimus 5 mg tablet, potentially reducing its effectiveness or causing unwanted side effects.
How to store Everolimus 5mg Tablet
References
FAQ - Everolimus
1What you should know before taking Everolimus 5mg tablet?
1. Inform Your Doctor About Your Health Conditions:
Tell your doctor if you have any liver or kidney problems, infection, or a history of lung or breathing issues.
If you have any allergies to Everolimus or other medicines, inform your doctor.
2. Medications You Are Taking:
Make sure to inform your doctor about all the medicines you’re taking, including prescription medications, over-the-counter drugs, vitamin or nutritional supplements, and herbal products. Some medications can interact with Everolimus and affect its effectiveness or cause side effects.
3. Pregnancy and Breastfeeding:
Everolimus can harm an unborn baby, so if you are pregnant or planning to become pregnant, talk to your doctor before using this medication.
If you are breastfeeding, inform your doctor, as Everolimus can pass into breast milk.
4. Fertility Concerns:
Everolimus may affect fertility in both men and women. If you are planning to have a child, consult your doctor beforehand.
5. Infection Risk:
Everolimus can weaken the immune system, increasing the risk of infections. Make sure to avoid contact with people who have infections, and report any symptoms of infection to your doctor.
6. Lab Tests and Monitoring:
Your doctor may recommend regular blood tests to monitor the effects of Everolimus on your body, including liver and kidney function.
7. Avoid Grapefruit:
Grapefruit and grapefruit juice may interact with Everolimus, so it's best to avoid them unless your doctor advises otherwise.
Make sure to follow your doctor’s instructions closely and discuss any concerns you have before starting treatment with Everolimus.
2Is it safe to use Everolimus tablet during pregnancy?
No, Everolimus is not considered safe to use during pregnancy.
Risk to the unborn baby: Everolimus may cause harm to a developing fetus and can increase the risk of birth defects or pregnancy complications.
Animal studies: Research in animals has shown negative effects on the fetus, and although human data is limited, the potential risks are significant.
Birth control recommended: Women of childbearing age should use effective contraception during treatment and for at least 8 weeks after the last dose of Everolimus.
If you are pregnant, planning to become pregnant, or think you might be pregnant, talk to your doctor immediately before taking this medicine.
3What are the side effects of Everolimus Tablet?
Common Side Effects of Everolimus Tablet:
Mouth ulcers or sores
Weakness or tiredness (fatigue)
Nausea or vomiting
Diarrhea
Loss of appetite
Cough or shortness of breath
Skin rash or itching
Increased risk of infections (due to weakened immune system)
Headache
Swelling in hands, feet, or ankles
High blood sugar (hyperglycemia)
Menstrual irregularities in women
Serious Side Effects (call your doctor immediately if you notice these):
Persistent fever, chills, or signs of infection
Difficulty breathing or chest pain
Severe mouth or throat pain
Unusual bleeding or bruising
Signs of allergic reaction: swelling, severe rash, itching, or trouble breathing
Because Everolimus affects the immune system and other body functions, regular monitoring through lab tests is usually needed during treatment.
4Is it safe to undergo surgery while on treatment with Everolimus tablet?
Caution is needed when undergoing surgery while taking Everolimus.
1. Delayed Wound Healing:Everolimus can slow down the body's ability to heal wounds, including surgical cuts, which increases the risk of infection and complications after surgery.
2. Higher Risk of Infection:
Because it weakens the immune system, Everolimus may raise the chance of infections during and after surgery.
3. What You Should Do:
Inform your surgeon and doctor well in advance if you're scheduled for any surgery.
Your doctor may decide to pause Everolimus before and after surgery to allow proper healing.
Never stop or change your medication without medical advice.
In summary: Everolimus can affect surgical outcomes, so always discuss planned procedures with your healthcare team.
1. Delayed Wound Healing:
5 Can I drink alcohol while taking Everolimus tablet?
It is generally advised to limit or avoid alcohol while taking Everolimus.
1. Liver strain:Both alcohol and Everolimus can affect liver function. Using them together may increase the risk of liver damage.
2. Weakened immune system:
Everolimus already lowers your immunity. Alcohol can further weaken your body’s defenses, raising the risk of infections.
3. Side effects may worsen:
Alcohol may increase side effects like fatigue, nausea, or dizziness when combined with Everolimus.
4. Interference with treatment:
Alcohol could potentially interfere with how well the medicine works, especially during cancer treatment or after an organ transplant.
Recommendation:
Talk to your doctor before consuming alcohol while on Everolimus. If allowed, it should be in moderation and only under medical advice.
1. Liver strain:
6What is Everolimus 5mg tablet used for?
Everolimus 5mg tablet is used to treat various types of cancers, including kidney, breast, and pancreatic neuroendocrine tumors. It’s also used for certain non-cancerous tumors in patients with tuberous sclerosis complex (TSC).
7What are the side effects of Everolimus 5mg?
Common side effects include mouth ulcers, fatigue, rash, infections, and low blood counts. Always consult your doctor if any severe or persistent side effects occur.
8How should Everolimus 5mg tablet be taken?
Everolimus 5mg should be taken once daily at the same time, with or without food. Swallow the tablet whole with water and follow your doctor’s instructions closely.
9Is Everolimus 5mg used for kidney cancer?
Yes, Everolimus 5mg is approved for the treatment of advanced kidney cancer (renal cell carcinoma), especially when other treatments have not worked.
10Can I buy Everolimus 5mg tablet online?
Yes, you can purchase Everolimus 5mg tablets online from licensed pharmacies or international suppliers. Always ensure you have a valid prescription before ordering.
11What is Everolimus 5mg tablet used for?
Everolimus 5mg tablet is prescribed to prevent organ rejection in kidney and liver transplant patients. It is also used in the treatment of certain cancers, including advanced breast cancer, kidney cancer, pancreatic neuroendocrine tumors, lung neuroendocrine tumors, and rare conditions like SEGA and renal angiomyolipoma associated with tuberous sclerosis.
12How should Everolimus 5mg tablet be taken?
Take Everolimus exactly as prescribed by your doctor. It is usually taken once daily at the same time, with or without food. Swallow the tablet whole with water — do not crush or chew. Dosage may vary depending on whether it is prescribed for cancer or transplant therapy.
13What are the common side effects of Everolimus 5mg tablet?
Common side effects include mouth sores, infections, rash, fatigue, diarrhea, decreased appetite, anemia, and changes in blood sugar or cholesterol levels. Most side effects are mild, but persistent or severe symptoms should be reported to your doctor immediately.
14What precautions should be taken while using Everolimus 5mg tablet?
Patients should inform their doctor about existing infections, liver problems, or other medications they are taking. Regular blood tests may be required to monitor health. Everolimus should be avoided during pregnancy and breastfeeding unless specifically advised by a doctor.
15What is the price of Everolimus 5mg tablet in India?
Prices vary depending on brand and manufacturer. Generic versions are more affordable compared to innovator brands like Afinitor. On average, Everolimus 5mg tablets are available in India around INR 6,000–7,000 per strip.
16Can Everolimus 5mg tablet be exported from India?
Yes, Everolimus 5mg tablets are available for bulk export worldwide. GMP‑certified suppliers provide HS code 30049099 compliance, proper SDS/MSDS documentation, and reliable logistics to ensure safe delivery to international buyers.
All Substitutes
Everolimus tablet brands in India
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Torinat 5mg tablet | 10 tablet | Natco Pharma | INR 2100 |
| Rolimus 5mg Tablet | 10 tablet | CIPLA Ltd | INR 4100 |
| Everbliss 5mg Tablet | 10 tablet | BDR Pharmaceuticals | INR 4100 |
| Evermil 5mg Tablet | 10 tablet | Glenmark Pharmaceuticals | INR 3500 |
Side Effects
Everolimus tablet side effects
- Infection (chills, increased temperature)
- Coughing
- Wheezing
- Excessive thirst
- High urine output or severely decreased urine output
- Tiredness
- Bleeding
- Increased appetite with weight loss
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