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Palbociclib 125mg Capsules (Kixta)
Original price was: $107.78.$53.25Current price is: $53.25.
United States dollar
Salt Composition: Palbociclib
Manufacturer: Zydus Cadila
Packaging Size: 21 Capsules
Delivery Services
Palbociclib 125mg Capsules – Overview & Benefits
Palbociclib 125mg capsules(Kixta) are used to treat a certain kind of breast cancer that is hormone-sensitive (estrogen receptor-positive) and HER2-negative, especially when it has spread to other parts of the body. It is usually taken along with hormone therapy for better results.
Take Palbociclib 125 mg capsule with food at the same time every day. Your doctor will decide the right dose and how often you should take it, depending on your health condition. Follow their instructions exactly. Do not take more or less than prescribed, as doing so may cause serious side effects.
It may take weeks or even months before you start feeling better, so don’t stop the medicine unless your doctor tells you to.
Before starting Palbociclib capsules, tell your doctor if you:
Have heart, liver, or kidney problems
Are taking medicine for any infections
Are using any other medications or supplements
Palbociclib can interact with many other drugs, so it’s important your doctor knows everything you’re taking.
Do not use this medicine if you are pregnant or breastfeeding. Use reliable birth control during treatment for both men and women to avoid pregnancy, as the medicine can harm an unborn baby.
Take Palbociclib 125 mg capsule with food at the same time every day. Your doctor will decide the right dose and how often you should take it, depending on your health condition. Follow their instructions exactly. Do not take more or less than prescribed, as doing so may cause serious side effects.
It may take weeks or even months before you start feeling better, so don’t stop the medicine unless your doctor tells you to.
Before starting Palbociclib capsules, tell your doctor if you:
Do not use this medicine if you are pregnant or breastfeeding. Use reliable birth control during treatment for both men and women to avoid pregnancy, as the medicine can harm an unborn baby.
Palbociclib 125mg capsule uses
Palbociclib 125 mg capsule is mainly used to treat certain types of advanced or metastatic breast cancer, specifically:
Estrogen receptor-positive (ER-positive)
HER2-negative (human epidermal growth factor receptor 2-negative)
It is not a standalone treatment. Palbociclib is given in combination with hormonal (endocrine) therapies such as:
Letrozole or other aromatase inhibitors (in postmenopausal women)
Fulvestrant (in women or men whose cancer has progressed after hormone therapy)
Palbociclib 125mg capsules benefits
1. Slows Cancer Growth
Palbociclib 125 mg capsules helps slow down the growth and spread of certain types of breast cancer by stopping cancer cells from multiplying.
2. Works with Hormone Therapy
When used with hormone-blocking medicines like Letrozole or Fulvestrant, it makes the treatment more effective.
3. Increases Time Without Cancer Progression
It can delay the worsening of cancer and give more time before the disease gets worse or spreads further.
4. Improves Quality of Life
By controlling the cancer for a longer time, it helps patients feel better and live more comfortably during treatment.
5. Oral Medicine (Capsule Form)
It is taken by mouth (not an injection), which makes it easier and more convenient for many patients.
Palbociclib 125 mg capsules helps slow down the growth and spread of certain types of breast cancer by stopping cancer cells from multiplying.
2. Works with Hormone Therapy
When used with hormone-blocking medicines like Letrozole or Fulvestrant, it makes the treatment more effective.
3. Increases Time Without Cancer Progression
It can delay the worsening of cancer and give more time before the disease gets worse or spreads further.
4. Improves Quality of Life
By controlling the cancer for a longer time, it helps patients feel better and live more comfortably during treatment.
5. Oral Medicine (Capsule Form)
It is taken by mouth (not an injection), which makes it easier and more convenient for many patients.
How Palbociclib 125mg capsule works
Our body has many types of cells that grow and divide, including cancer cells. In some types of breast cancer, these cancer cells grow faster because of hormones like estrogen.
1. Hormone-blocking medicines (like Letrozole or Fulvestrant) stop estrogen from helping the cancer grow.
2. Palbociclib adds extra help — it blocks special proteins in the body called CDK4 and CDK6. These proteins help cells divide and grow.
By blocking these proteins, Palbociclib slows down or stops cancer cells from growing and spreading.
1. Hormone-blocking medicines (like Letrozole or Fulvestrant) stop estrogen from helping the cancer grow.
2. Palbociclib adds extra help — it blocks special proteins in the body called CDK4 and CDK6. These proteins help cells divide and grow.
By blocking these proteins, Palbociclib slows down or stops cancer cells from growing and spreading.
How to use Palbociclib 125mg capsule
1. Take Once a Day
Take Palbociclib 125 mg capsule once daily, exactly as your doctor tells you.
2. Take With Food
Always take it with food (breakfast or lunch). This helps your body absorb the medicine better.
3. Same Time Every Day
Try to take it at the same time each day to help remember your dose.
4. Treatment Cycle
Usually, you take the medicine for 21 days (3 weeks), then stop for 7 days (1 week off). This is called a 28-day cycle. Your doctor will guide you.
5. Swallow Whole
Swallow the capsule whole with water. Do not chew, crush, or open the capsule.
6. Missed Dose?
If you miss a dose and it's less than 12 hours late, take it right away.
If it's more than 12 hours late, skip that dose. Do not take two doses at once.
7. Do Not Stop on Your Own
Keep taking it even if you feel well. Only stop if your doctor tells you to.
Your doctor may also ask for regular blood tests to check your blood counts while on this medicine.
Take Palbociclib 125 mg capsule once daily, exactly as your doctor tells you.
2. Take With Food
Always take it with food (breakfast or lunch). This helps your body absorb the medicine better.
3. Same Time Every Day
Try to take it at the same time each day to help remember your dose.
4. Treatment Cycle
Usually, you take the medicine for 21 days (3 weeks), then stop for 7 days (1 week off). This is called a 28-day cycle. Your doctor will guide you.
5. Swallow Whole
Swallow the capsule whole with water. Do not chew, crush, or open the capsule.
6. Missed Dose?
Keep taking it even if you feel well. Only stop if your doctor tells you to.
Your doctor may also ask for regular blood tests to check your blood counts while on this medicine.
Palbociclib 125mg capsule Dosage & Administration
The standard dosage is one 125mg capsule taken once daily for 21 days, followed by 7 days off. Always consult your oncologist before starting treatment.
Therapeutic Effects of Kixta Palbociclib 125mg Capsules
Kixta 125mg capsule functions by inhibiting the activity of cyclin-dependent kinases 4 and 6, essential for cell division and growth. This action slows cell growth and impedes the spread of cancer cells.
Interaction of Palbociclib 125mg capsule with other drugs
Palbociclib 125 mg capsule can interact with many other medicines. This means some drugs can:
Make Palbociclib less effective, or
Increase the risk of side effects
So it’s very important to tell your doctor about all medicines, supplements, or herbal products you are taking before starting Palbociclib.
What You Should Do:Always tell your doctor or pharmacist about all the medicines you are using — even over-the-counter ones.
Don’t start or stop any medicine without talking to your doctor.
What You Should Do:
More Information about Palbociclib Capsule
Fact Box of Palbociclib capsule
References
FAQ - Palbociclib
1Is Palbociclib 125mg capsule a form of targeted therapy?
2Is hair loss a common side effect of the Palbociclib 125mg capsule?
Yes, hair thinning or hair loss (also called alopecia) is a common side effect of Palbociclib 125 mg capsule but it's usually mild to moderate, not complete baldness like with some chemotherapy drugs.
Many patients experience thinning of hair rather than full hair loss.
Hair loss is often temporary — hair may grow back after the treatment ends or even during treatment.
Not everyone will lose hair — the effect varies from person to person.
Taking Palbociclib with Letrozole or Fulvestrant may increase this side effect.
Tips to Manage Hair Thinning:
Use a mild shampoo and avoid harsh chemicals or heat styling.
Be gentle while brushing and washing your hair.
Talk to your doctor if hair loss is bothering you sometimes they may adjust the dose.
3Is Palbociclib 125mg capsule suitable for use in children?
No, Palbociclib 125 mg capsules are not suitable for use in children.
Palbociclib is approved only for adults, especially for treating certain types of breast cancer in adults.
Safety and effectiveness in children have not been studied well, so it is not recommended for use in anyone under 18 years of age.
Using it in children could cause unknown or harmful side effects.
What to Do:
Always follow your doctor’s advice.
Never give Palbociclib to a child unless a specialist clearly advises and supervises it.
What to Do:
4Can Palbociclib 125mg capsule impact fertility?
Yes, Palbociclib 125 mg capsules may affect fertility, especially in men.
In men, Palbociclib may lower sperm count or affect sperm quality, which can reduce the ability to father a child.
In women, the effect on fertility is not clearly known, but there's a possibility it could affect the ovaries and reduce fertility.
Important Advice:
1. Men who wish to have children in the future should consider sperm banking before starting treatment.
2. Women should discuss fertility concerns with their doctor before starting Palbociclib.
3. Use effective birth control during treatment and for some time after, as the medicine can harm an unborn baby.
Always talk to your doctor: If you are planning for a family or have concerns about future fertility, your doctor can guide you about options like fertility preservation.
Important Advice:
1. Men who wish to have children in the future should consider sperm banking before starting treatment.
2. Women should discuss fertility concerns with their doctor before starting Palbociclib.
3. Use effective birth control during treatment and for some time after, as the medicine can harm an unborn baby.
Always talk to your doctor: If you are planning for a family or have concerns about future fertility, your doctor can guide you about options like fertility preservation.
5Can Palbociclib 125mg capsule affect blood cell count?
Yes, Palbociclib 125 mg capsules can affect blood cell counts, and this is one of the most common side effects.
Palbociclib works by slowing down the growth of fast-dividing cells — including cancer cells but also some normal cells like blood-forming cells in the bone marrow.
As a result, it can lower your blood counts, especially:
1. White blood cells (neutrophils)
These help fight infections. A low count (neutropenia) increases the risk of infections.
2. Red blood cells
These carry oxygen. A low count can cause tiredness, weakness, or shortness of breath (called anemia).
3. Platelets
These help blood clot. A low count may lead to easy bruising or bleeding.
What You Should Do:Your doctor will do regular blood tests (usually before each cycle) to check your blood counts.
If your counts are too low, your doctor may:
Delay or adjust the dose
Pause treatment for a few days
Recommend supportive care
Tell your doctor immediately if you have:
Fever or signs of infection
Unusual tiredness
Easy bruising or bleeding
Palbociclib works by slowing down the growth of fast-dividing cells — including cancer cells but also some normal cells like blood-forming cells in the bone marrow.
As a result, it can lower your blood counts, especially:
1. White blood cells (neutrophils)
These help fight infections. A low count (neutropenia) increases the risk of infections.
2. Red blood cells
These carry oxygen. A low count can cause tiredness, weakness, or shortness of breath (called anemia).
3. Platelets
These help blood clot. A low count may lead to easy bruising or bleeding.
What You Should Do:
Tell your doctor immediately if you have:
6Palbociclib brand name
Palbociclib brand name
7Palbociclib mechanism of action
Palbociclib machanism of action
In cancer cells that have a working (functional) retinoblastoma (RB) tumor suppressor gene, Palbociclib stops cell growth and DNA replication by blocking CDK4 and CDK6, which are needed for cells to move from the G1 phase to the S phase of the cell cycle.8Palbociclib side effects
Palbociclib side effects
1. Tiredness 2. Hair loss 3. Dry skin, rash 4. Infections 5. Low blood cell counts 6. Decreased of appetite 7. Nausea, vomiting 8. Diarrhea 9. Swelling of lips and mouth 10. Changes in taste 11. Nose bleed 12. Dry eye, blurred vision, increased tearing9Palbociclib cost
Palbociclib cost
INR 310010Palbociclib prescribing information
Palbociclib prescribing information
1. IndicationsPalbociclib is indicated for adults with:
1. Neutropenia:
2. Infections:
Most common (≥ 20%)
Palbociclib is a selective CDK4/6 inhibitor that prevents phosphorylation of retinoblastoma (RB) protein, blocking G1→S phase transition and inhibiting tumor cell proliferation.
10. Storage
11Palbociclib price
Palbociclib price
INR 310012What is the price of Palbociclib 125mg capsule in India?
The price of Palbociclib 125mg capsules in India varies depending on the brand and supplier. We offer competitive wholesale rates and export options. Contact us for the latest pricing.
13Can I buy Palbociclib capsules online?
Yes, you can buy Palbociclib capsules online through verified pharmaceutical distributors in India. We provide secure packaging and worldwide shipping for bulk and individual orders.
14What are the uses of Palbociclib capsules in breast cancer?
Palbociclib is used to treat HR-positive, HER2-negative advanced or metastatic breast cancer, often in combination with hormone therapy like letrozole or fulvestrant.
15What are the side effects of Palbociclib 125mg capsules?
Common side effects include fatigue, nausea, decreased white blood cell count, and infections. Patients should be monitored regularly by their doctor during treatment.
16Do you supply Palbace Palbociclib 125mg Capsules in bulk for export?
Yes, Palbace Palbociclib 125mg Capsules are available for bulk export orders with GMP certification, proper documentation, and reliable logistics support.
17What is the price of Palbace Palbociclib 125mg Capsules in India?
Prices vary depending on manufacturer and pack size. Competitive quotations are provided for domestic buyers and export clients.
18What is the HS code for Palbace Palbociclib 125mg Capsules?
The HS code commonly used is 30049099, applicable for customs clearance and international trade documentation.
19Are Indian suppliers reliable for Palbace Palbociclib 125mg Capsules exports?
Yes, India is a trusted supplier of oncology medicines, offering Palbace Palbociclib 125mg Capsules with compliance to global quality standards.
20Do you provide worldwide shipping for Palbace Palbociclib 125mg Capsules?
Yes, we ship Palbace Palbociclib 125mg Capsules globally with customs clearance support and timely delivery to major export destinations.
All Substitutes
Palbociclib brands in india
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Ciclib 125mg capsule | 21 capsule | Shilpa Medicare | INR 2700 |
| Piclib 125mg capsule | 21 capsule | Hetero Healthcare | INR 3100 |
| Bdpalbo 125mg capsule | 21 capsule | BDR Pharmaceuticals | INR 3200 |
| Palbocib 125mg capsule | 21 capsule | Aprazer Healthcare | INR 4000 |
| Palnat 125mg capsule | 21 capsule | Natco Pharma | INR 2980 |
| Piciclib 125mg capsule | 21 capsule | Cipla Ltd | INR 4050 |
| Palbace 125mg capsule | 21 capsule | Pfizer Ltd | INR 17900 |
Side Effects
Palbociclib side effects
- Tiredness
- Hair loss
- Dry skin, rash
- Infections
- Low blood cell counts
- Decreased of appetite
- Nausea, vomiting
- Diarrhea
- Swelling of lips and mouth
- Changes in taste
- Nose bleed
- Dry eye, blurred vision, increased tearing
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