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Sirolimus 1 mg Tablets (Siromus)
Original price was: $15.92.$8.25Current price is: $8.25.
United States dollar
Sirolimus 1mg Tablets (Siromus) – Overview & Benefits
Sirolimus 1mg Tablets (Siromus) are used for transplant recipients to prevent organ rejection. It functions by regulating the body's immune response, allowing the transplanted organ to be accepted.
You should take sirolimus 1mg tablet according to the prescribed dose and duration. You can consume it with or without food, but it's crucial to maintain consistency in timing each day. Taking more than the prescribed dose can cause severe side effects on the body.
Before consuming this medication, it is important to consult with your doctor, especially if you are currently undergoing treatment for any underlying condition. Pregnant or breastfeeding women should inform their doctor before starting this therapy. Throughout the treatment course, your doctor may recommend periodic laboratory tests to monitor the medicine's impact on your body. If you notice symptoms such as infection, alterations in mole appearance or size, abnormal growths or lumps, or unusual fatigue or weakness, it is important that you seek medical advice immediately.
You should take sirolimus 1mg tablet according to the prescribed dose and duration. You can consume it with or without food, but it's crucial to maintain consistency in timing each day. Taking more than the prescribed dose can cause severe side effects on the body.
Before consuming this medication, it is important to consult with your doctor, especially if you are currently undergoing treatment for any underlying condition. Pregnant or breastfeeding women should inform their doctor before starting this therapy. Throughout the treatment course, your doctor may recommend periodic laboratory tests to monitor the medicine's impact on your body. If you notice symptoms such as infection, alterations in mole appearance or size, abnormal growths or lumps, or unusual fatigue or weakness, it is important that you seek medical advice immediately.
Uses of Sirolimus 1 mg tablet
Benefits of Sirolimus 1 mg tablet
Preventing kidney transplant rejection
To prevent kidney transplant rejection, physicians use Sirolimus 1mg tablet along with other medications. Typically, rejection occurs when the recipient's immune system attacks the transplanted organ. This medication reduces the activity of the individual's immune system in kidney transplant recipients, preventing rejection episodes.How to use Sirolimus 1 mg tablet
Follow your doctor's guidance regarding the dosage and duration of this medication. Swallow the tablet whole; avoid chewing, crushing, or breaking it. You can take the Sirolimus 1mg tablet with or without food, but it's advisable to maintain a consistent time for administration.
How Sirolimus 1 mg table works
Sirolimus 1mg tablet acts as an immunosuppressant, functioning to suppress your body's immune response subsequent to an organ transplant (e.g., liver, kidney, heart). This mechanism allows your body to accept the new organ as if it were native.
Therapeutic Effects of Siromus Sirolimus 1 mg tablet
Siromus 1mg tablet is an immunosuppressant that reduces your body's immune system activity, shielding the transplanted organ from attack.
Sirolimus 1 mg tablet compatibility with other medications
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products you are currently taking or have taken before starting treatment. Some medications may interact with the Sirolimus 1mg tablet, potentially reducing its effectiveness and leading to undesirable side effects.
More Information about Sirolimus tablet
References
FAQ - Siromus
1Will Sirolimus 1 mg Tablet affect fertility?
Sirolimus 1mg tablets can decrease the sperm count, which returns to a normal state after treatment. For more fertility concerns, talk with your doctor.
2Can Sirolimus 1 mg Tablet cause any injury to the kidney?
Sirolimus 1mg tablets can damage the kidneys, with or without rashes (hemolytic uraemic syndrome). Talk with your doctor before starting this medicine.
3What should I be aware of before taking Sirolimus 1 mg Tablet?
If you are intolerant of some sugars, like lactose and sucrose, inform your doctor before the treatment. Additionally, avoid taking the Sirolimus 1mg Tablet with grapefruit or its juice.
4Can Sirolimus 1 mg Tablet, cause diabetics?
The sirolimus 1mg tablet may affect blood sugar levels. So, regularly check your blood sugar levels and notify your doctor if there are any sudden changes.
5What should I inform my doctor before starting the Sirolimus 1 mg Tablet treatment?
Inform your doctor if you have any history of lung or liver transplantation or hypersensitivity, because sirolimus 1mg tablets are not recommended in such cases.
6Sirolimus drug
Sirolimus drug
One type of immunosuppressant called sirolimus is a mTOR inhibitor. It is used to treat lymphangioleiomyomatosis, stop organ transplant rejection, and help adults with perivascular epithelioid cell tumors.7Sirolimus side effects
Sirolimus side effects
1. Abnormal vision.2. acne.
3. belching.
4. The skin may experience blistering, crusting, irritation, itching, or reddening. There is a burning feeling in the chest or stomach.
5. There may be sensations of burning, crawling, itching, numbness, prickling, "pins and needles," or tingling.
6. constipation.
7. There is a persistent ringing, buzzing, or other unexplained noise in the ears.
8Sirolimus mechanism of action
Sirolimus mechanism of action
Sirolimus combines with the intracellular protein FKBP12 to create an immunosuppressive complex. This complex blocks the activation of TOR, a cell-cycle-specific kinase. Consequently, this complex obstructs cell-cycle progression at the G1 and S phase junctions.9Sirolimus vs Tacrolimus
Sirolimus vs Tacrolimus
The 1-year graft survival rate was 92% in the tacrolimus group and 94% in the sirolimus group, according to the Kaplan-Meier estimate (p = 0.95; Figure 1B). Death-censored 1-year graft survival rates were 96% in the tacrolimus group and 96% in the sirolimus group (p = 0.96).10Sirolimus brand name
Sirolimus brand name
1. Rocas 1mg tablet2. Sirova 1mg tablet
3. Rapacan 1mg tablet
4. Repamune
11Sirolimus moa
Sirolimus moa
Its main mode of action involves inhibiting the mammalian target of rapamycin (mTOR), a protein kinase crucial for regulating cell growth, proliferation, and survival.12Tacrolimus vs Sirolimus
Tacrolimus vs Sirolimus
The 1-year graft survival rate was 92% in the tacrolimus group and 94% in the sirolimus group, according to the Kaplan-Meier estimate (p = 0.95; Figure 1B). Death-censored 1-year graft survival rates were 96% in the tacrolimus group and 96% in the sirolimus group (p = 0.96).13Sirolimus cost
Sirolimus cost
Sirolimus cost: INR 550/strip14Mechanism of action of sirolimus
Mechanism of action of sirolimus
Sirolimus combines with the intracellular protein FKBP12 to create an immunosuppressive complex. This complex blocks the activation of TOR, a cell-cycle-specific kinase. Consequently, this complex obstructs cell-cycle progression at the G1 and S phase junctions.15Sirolimus 0.5 mg tablet
Sirolimus 0.5 mg tablet
Sirolimus 0.5 mg tablet: INR 550/strip16What are Sirolimus tablets used for?
Sirolimus is primarily used to prevent organ rejection after kidney transplantation. It is also prescribed for certain rare lung disorders like lymphangioleiomyomatosis (LAM).
17How should Sirolimus tablets be taken?
Sirolimus is taken orally once daily, usually in combination with other immunosuppressants such as cyclosporine and corticosteroids. The exact dose depends on the patient’s condition and must be adjusted by a doctor.
18What are the common side effects of Sirolimus?
Common side effects include mouth ulcers (stomatitis), infections, high cholesterol, delayed wound healing, anemia, and swelling. Serious risks may include lung inflammation, blood clotting, and kidney problems.
19How does Sirolimus work?
Sirolimus is an mTOR inhibitor. It suppresses the immune system by blocking T‑cell activation and proliferation, thereby preventing the body from rejecting a transplanted organ.
20What precautions should be taken while using Sirolimus tablets?
Patients should undergo regular blood tests to monitor kidney function, cholesterol, and blood counts. Avoid live vaccines during treatment. Sirolimus can increase the risk of infections and certain cancers, so medical supervision is essential.
All Substitutes
Sirolimus 1mg brands in india
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Rocas 1mg tablet | 6 tablets | Emcure Pharmaceuticals | INR 400 |
| Sirova 1mg tablet | 10 tablets | Intas Pharmaceuticals | INR 850 |
| Rapacan 1mg tablet | 10 tablets | Biocon Ltd | INR 890 |
Side Effects
Sirolimus side effects
- Nausea
- Increased blood lipid level
- Low blood platelets
- Headache
- Abdominal pain
- Fever
- Anemia (low number of red blood cells)
- Urinary tract infection
- Diarrhea
- High blood pressure
- Increased creatinine level in blood
- Joint pain
- Edema (swelling)
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