Abirapro Abiraterone Acetate 250mg tablet is prescribed to manage prostate gland cancer. It may also be used to treat other conditions, as determined by the doctor. In some cases, it is integrated with specific medications as part of combination chemotherapy.
You should not accept the Abirapro Abiraterone Acetate 250mg tablet on an empty stomach, as doing so with food may cause side effects. Your doctor will choose the proper dosage and frequency based on the particular condition you are treating, and these guidelines might change over time. It is crucial to follow your doctor's guidance regarding the exact way to take the medication, as improper usage or excessive intake can result in severe side effects. Since it may take weeks or months to see results, don't stop taking the medication unless your doctor says so.
Prior to initiating this medication, inform your doctor of any pre-existing conditions, such as high blood pressure, heart issues, liver or kidney problems, or similar use of medications for treating infections. Give your doctor a thorough list of all the medications you are currently taking, because many other drugs may interact with or impact this one. During pregnancy and breastfeeding, avoid this medication because it may harm your baby. We advise both males and females to use effective contraception throughout the treatment to prevent pregnancy. Additionally, regular monitoring of your blood glucose level may be required during the course of treatment.
Abiraterone Acetate tablet uses
1. Prostate cancer
Abiraterone Acetate tablet benefits
Prostate Cancer
The prostate gland, a small, walnut-sized organ, generates seminal fluid vital for nourishing and transporting sperm in males. Prostate cancer often indicates urinary difficulties as a primary symptom, though it can also be asymptomatic. Abirapro Abiraterone Acetate 250mg tablet slows down or stops the growth of cancer cells by lowering testosterone levels, which is a natural hormone found in men. This action alleviates urination challenges, allowing for a smoother and more comfortable urinary process.
How to use Abiraterone Acetate 250mg tablet
Follow your doctor's guidance regarding the dosage and duration of this medication. Swallow the tablet whole, without chewing, crushing, or breaking it. Take the Abirapro Abiraterone Acetate 250mg tablet on an empty stomach.
How Abiraterone Acetate tablet works
Abirapro Abiraterone Acetate 250mg tablet is an anticancer drug that functions by blocking the production of androgen (the male hormone) in men. It achieves this by inhibiting the activity of an enzyme (CYP17) responsible for androgen production. As a result, it slows down the progression of prostate cancer.
Dosage and Administration
ABIRATERONE ACETATE 1,000 mg (four 250 mg tablets) was administered orally once daily in combination with prednisone 5 mg, which was administered orally twice daily. ABIRATERONE ACETATE must be taken on an empty stomach. No food should be consumed for at least two hours before and one hour after taking the dose.
The tablets should be swallowed whole with water. Do not crush or chew the tablets.
For patients with baseline moderate hepatic impairment (Child-Pugh Class B), the starting dose of ABIRATERONE ACETATE should be reduced to 250 mg once daily.
For patients who develop hepatotoxicity during treatment, ABIRATERONE ACETATE should be temporarily discontinued until recovery. Retreatment may be initiated at a reduced dose. However, ABIRATERONE ACETATE should be permanently discontinued if the patient develops severe hepatotoxicity.
Therapeutic Effects of Abiraterone Acetate tablet
Abiraterone acetate 250 mg functions by suppressing the synthesis of the hormone testosterone, impeding the progression of prostate cancer, and slowing its growth.
Abiraterone Acetate Tablet compatibility with other medications
Ensure you inform your doctor about any prescribed medications, over-the-counter drugs, nutritional and vitamin supplements, as well as herbal products you are currently taking or have used prior to initiating the treatment. Some medications may interact with Abirapro 250mg tablets, potentially leading to unwanted side effects.
More Information about Abiraterone Acetate tablet
1. This medication does not necessitate specific storage conditions.
2. Please keep it out of children's sight and reach.
Special population
Pregnancy and Lactation
ABIRATERONE ACETATE can cause fetal harm when administered to a pregnant woman, based on its mechanism of action and findings in animal studies. While there are no adequate and well-controlled studies of ABIRATERONE ACETATE in pregnant women and it is not indicated for use in women, it is important to recognize that maternal use of a CYP17 inhibitor could affect fetal development.
Abiraterone acetate caused developmental toxicity in pregnant rats at exposures lower than those observed in patients receiving the recommended dose. ABIRATERONE ACETATE is contraindicated in women who are pregnant or may become pregnant while receiving the drug.
If this drug is used during pregnancy, or if a patient becomes pregnant while taking it, the patient should be informed of the potential hazard to the fetus and the risk of pregnancy loss. Advise females of reproductive potential to avoid becoming pregnant during treatment with ABIRATERONE ACETATE.
Nursing Mothers
ABIRATERONE ACETATE is not indicated for use in women. It is unknown whether abiraterone acetate is excreted in human milk. Because many drugs can be excreted in human milk and may affect nursing infants, a decision should be made to either discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Adverse Reactions
The most common adverse reactions (>10%) are fatigue, joint swelling or discomfort, edema, hot flush, diarrhea, vomiting, cough, hypertension, dyspnea, urinary tract infection, and contusion.
The most common laboratory abnormalities (>20%) are anemia, elevated alkaline phosphatase, hypertriglyceridemia, lymphopenia, hypercholesterolemia, hyperglycemia, elevated AST, hypophosphatemia, elevated ALT, and hypokalemia.
Two randomized, placebo-controlled, multicenter clinical trials enrolled patients with metastatic castration-resistant prostate cancer (mCRPC) who were receiving a gonadotropin-releasing hormone (GnRH) agonist or had previously undergone orchiectomy. In both studies, ABIRATERONE ACETATE was administered at a dose of 1,000 mg once daily in combination with prednisone 5 mg twice daily in the active treatment arm. The control patients received placebo plus prednisone 5 mg twice daily.
The most common adverse drug reactions (>10%) reported in the two randomized clinical trials that occurred more frequently (>2%) in the abiraterone acetate arm were fatigue, joint swelling or discomfort, edema, hot flush, diarrhea, vomiting, cough, hypertension, dyspnea, urinary tract infection, and contusion.
The most common laboratory abnormalities (>20%) reported in the two randomized clinical trials that occurred more frequently (>2%) in the abiraterone acetate arm were anemia, elevated alkaline phosphatase, hypertriglyceridemia, lymphopenia, hypercholesterolemia, hyperglycemia, elevated AST, hypophosphatemia, elevated ALT, and hypokalemia.
One study enrolled 1,195 patients with metastatic CRPC who had previously received docetaxel chemotherapy. Patients were not eligible if AST and/or ALT exceeded 2.5× the upper limit of normal (ULN) in the absence of liver metastases. Patients with liver metastases were excluded if AST and/or ALT exceeded 5× ULN.
Table 1 shows adverse reactions in the ABIRATERONE ACETATE arm in one study that occurred with a >2% absolute increase in frequency compared to placebo or were events of special interest. The median duration of treatment with ABIRATERONE ACETATE was 8 months.
1What is the recommended method for consuming Abiraterone Acetate (abirapro) 250mg tablet?
Follow the doctor's prescription when taking an Abirapro 250mg tablet on an empty stomach. Eat at least 2 hours before taking the medication, and wait 1 hour afterward to eat.
2Is the Abiraterone Acetate (abirapro) 250mg tablet capable of curing prostate cancer?
Abiraterone acetate (abirapro) 250mg tablet does not provide a cure for prostate cancer; rather, it is used in the treatment of prostate cancer that has metastasized. Typically, doctors prescribe this drug in the early stages of the condition, combining it with testosterone-lowering therapy to minimize potential side effects.
3Does the use of Abiraterone Acetate (abirapro) 250mg tablets exacerbate liver conditions?
Abiraterone Acetate (abirapro) 250mg tablet is discouraged for individuals with severe liver conditions, as it may make the condition worse. Before using this medication, patients should inform their doctor about any existing liver disorders.
4What is the mechanism of action of the Abiraterone Acetate (abirapro) 250mg tablet?
Abiraterone acetate (abirapro) 250mg tablet, an anticancer medication, functions by inhibiting the production of androgens and blocking the enzyme responsible for their integration.
5Is Abiraterone Acetate (abirapro) 250mg tablet a chemotherapy drug?
Abiraterone Acetate (abirapro) 250mg tablet is not a chemotherapy drug; rather, it is a hormonal treatment employed for prostate cancer. It acts by inhibiting testosterone production, thereby mitigating the growth of prostate cancer.
6What potential side effects may arise from the use of the Abiraterone Acetate 250mg tablet?
Common side effects of the Abiraterone Acetate (abirapro) 250mg tablet include edema (fluids in the legs), decreased blood potassium levels, elevated blood pressure, urinary tract infections, an irregular heartbeat, diarrhea, skin rashes, and indigestion.
7Abiraterone acetate india
Abiraterone acetate india
The attending physician prescribes abiraterone acetate for the treatment of prostate gland cancer and may also use it to address other medical conditions as deemed appropriate. Additionally, the attending physician occasionally incorporates it into combination chemotherapy protocols in collaboration with other medications.
8What is abiraterone acetate used for
What is abiraterone acetate used for
Prostate cancer
9What is abiraterone acetate
What is abiraterone acetate
Males with prostate cancer receive prescriptions for the medication abiraterone acetate.
10What does abiraterone acetate do
What does abiraterone acetate do
Abiraterone acetate prevents the growth of cancer cells in men by reducing testosterone levels, a natural male hormone. Additionally, it reduces discomfort in the urinary area and facilitates easier urination.
11Does abiraterone acetate cure prostate cancer
Does abiraterone acetate cure prostate cancer
While abiraterone won't cure prostate cancer, it is effective in managing and controlling the disease, and studies have demonstrated its ability to extend the lifespan of some men. Additionally, it aids in treating or postponing symptoms such as pain and fatigue.
12How does abiraterone acetate work
How does abiraterone acetate work
Abiraterone functions by inhibiting the production of the hormone testosterone, using a unique mechanism compared to other forms of hormone therapy. For the majority of men, prostate cancer cells are unable to grow without testosterone, even if they have metastasized to other areas of the body.
13How long should abiraterone acetate be taken
How long should abiraterone acetate be taken
Prednisone and abiraterone acetate work together as a hormone therapy to treat metastasized prostate cancer. Patients generally continue taking medications like Zelgor, Abirapro, Arbitus, Xbira, Zytiga, Samtica, Abiratred, etc., for as long as they prove effective or are tolerable.
14How to take abiraterone acetate
How to take abiraterone acetate
Abiraterone is available in tablet form for oral consumption on an empty stomach with water, either 1 hour before or 2 hours after eating. One should typically take Abiraterone once or twice daily, ideally at approximately the same time each day.
15Is abiraterone acetate covered by medicare
Is abiraterone acetate covered by medicare
Definitaly. All Medicare prescription drug plans include coverage for this medication, ensuring comprehensive access.
