-25%
Herduo 250mg tablet
Original price was: ₹6,000.00.₹4,500.00Current price is: ₹4,500.00.
Indian rupee (₹) - INR
Salt Composition: Lapatinib
Manufacturer: Natco Pharma
Packaging Size: 30 Tablet
Delivery Services
Herduo Lapatinib 250 Mg Tablet
Herduo Lapatinib 250 Mg Tablet is used to treat breast cancer. It helps by slowing down or stopping the growth of cancer cells. It can be taken by itself or with other medicines, especially for advanced breast cancer.
Take Lapatinib Tablet on an empty stomach — either 1 hour before a meal or 2 hours after. Your doctor will decide the right dose and how long you need to take it, based on your condition. Make sure to take it exactly as your doctor says to avoid serious side effects. It might take weeks or even months to feel better, but don’t stop taking it unless your doctor tells you to.
Before you start taking Lapatinib Tablet, tell your doctor if you have any liver or kidney problems. Also, let your doctor know about all other medicines you are using, as they may interact with lapatinib.
Do not take this medicine if you are pregnant or breastfeeding. Both men and women should use reliable birth control during treatment to avoid pregnancy.
Take Lapatinib Tablet on an empty stomach — either 1 hour before a meal or 2 hours after. Your doctor will decide the right dose and how long you need to take it, based on your condition. Make sure to take it exactly as your doctor says to avoid serious side effects. It might take weeks or even months to feel better, but don’t stop taking it unless your doctor tells you to.
Before you start taking Lapatinib Tablet, tell your doctor if you have any liver or kidney problems. Also, let your doctor know about all other medicines you are using, as they may interact with lapatinib.
Do not take this medicine if you are pregnant or breastfeeding. Both men and women should use reliable birth control during treatment to avoid pregnancy.
Uses of Lapatinib Tablet
Lapatinib Tablet is mainly used to treat certain types of breast cancer. Specifically, it is used for:
1. HER2-positive breast cancer – a type of breast cancer where cancer cells have more HER2 proteins, which help them grow faster.
2. Advanced or metastatic breast cancer – when the cancer has spread to other parts of the body.
3. Often used in combination with other cancer medicines like capecitabine or letrozole for better effectiveness.
It works by blocking HER2 receptors, helping to stop or slow down the growth of cancer cells.
1. HER2-positive breast cancer – a type of breast cancer where cancer cells have more HER2 proteins, which help them grow faster.
2. Advanced or metastatic breast cancer – when the cancer has spread to other parts of the body.
3. Often used in combination with other cancer medicines like capecitabine or letrozole for better effectiveness.
It works by blocking HER2 receptors, helping to stop or slow down the growth of cancer cells.
Benefits of Lapatinib Tablet
1. Slows cancer growth – Lapatinib helps stop the growth and spread of HER2-positive breast cancer cells.
2. Effective in advanced cancer – It is especially helpful in treating breast cancer that has spread to other parts of the body.
3. Works when other treatments fail – It may still work even if other cancer treatments have stopped working.
4. Can be combined with other drugs – When used with medicines like capecitabine or letrozole, it can improve overall treatment results.
5. Targets cancer cells specifically – It blocks specific proteins (HER2 and EGFR) that help cancer cells grow, without harming most healthy cells.
2. Effective in advanced cancer – It is especially helpful in treating breast cancer that has spread to other parts of the body.
3. Works when other treatments fail – It may still work even if other cancer treatments have stopped working.
4. Can be combined with other drugs – When used with medicines like capecitabine or letrozole, it can improve overall treatment results.
5. Targets cancer cells specifically – It blocks specific proteins (HER2 and EGFR) that help cancer cells grow, without harming most healthy cells.
Uses of Lapatinib Tablet
Lapatinib Tablet is used to treat HER2-positive breast cancer, especially when:
1. The cancer has spread to other parts of the body (advanced or metastatic stage).
2. It is used after other treatments haven’t worked well.
3. It is often given with other medicines like capecitabine or letrozole to improve results.
It works by blocking proteins (HER2 and EGFR) that help cancer cells grow.
1. The cancer has spread to other parts of the body (advanced or metastatic stage).
2. It is used after other treatments haven’t worked well.
3. It is often given with other medicines like capecitabine or letrozole to improve results.
It works by blocking proteins (HER2 and EGFR) that help cancer cells grow.
How Lapatinib Tablet Works
Lapatinib is a type of targeted cancer medicine. It works by:
1. Blocking two proteins — HER2 and EGFR — that are found in some cancer cells.
2. These proteins normally help cancer cells grow and divide quickly.
3. By blocking them, Lapatinib slows down or stops the growth of the cancer cells.
This helps in controlling the spread of HER2-positive breast cancer, especially in advanced stages.
1. Blocking two proteins — HER2 and EGFR — that are found in some cancer cells.
2. These proteins normally help cancer cells grow and divide quickly.
3. By blocking them, Lapatinib slows down or stops the growth of the cancer cells.
This helps in controlling the spread of HER2-positive breast cancer, especially in advanced stages.
Therapeutic Effects of Herduo Lapatinib Tablet
Herduo 250mg Tablet works by blocking an enzyme called tyrosine kinase. This enzyme helps cancer cells grow. The tablet stops signals from special proteins called HER2 and EGFR, which are made in large amounts by some breast cancer cells. By blocking these signals, Herduo kills cancer cells and slows their growth.
How to store Lapatinib Tablet
Interaction of Lapatinib Tablet with other drugs
1. Other cancer treatments – Certain chemotherapy or cancer medications may affect how Hertab works.
2. Antifungal medicines – Drugs like ketoconazole can interfere with Hertab’s effectiveness.
3. Antibiotics – Some antibiotics, such as clarithromycin, may increase the side effects of Hertab.
4. Medicines for heart conditions – Drugs like digoxin may have altered effects when taken with Hertab.
5. Blood thinners – Medications like warfarin may interact with Hertab and affect your blood clotting.
2. Antifungal medicines – Drugs like ketoconazole can interfere with Hertab’s effectiveness.
3. Antibiotics – Some antibiotics, such as clarithromycin, may increase the side effects of Hertab.
4. Medicines for heart conditions – Drugs like digoxin may have altered effects when taken with Hertab.
5. Blood thinners – Medications like warfarin may interact with Hertab and affect your blood clotting.
How Lapatinib Tablet works
Lapatinib Tablet contains Lapatinib, which is a targeted cancer medicine. It works in the following way:
1. Blocks cancer signals – It stops two proteins, HER2 and EGFR, that help cancer cells grow and multiply.
2. These proteins are often found in large amounts in certain breast cancer cells.
3. By blocking these signals, Hertab helps to slow down the growth of cancer cells and can even kill them.
This helps control the spread of HER2-positive breast cancer, especially in advanced stages.
1. Blocks cancer signals – It stops two proteins, HER2 and EGFR, that help cancer cells grow and multiply.
2. These proteins are often found in large amounts in certain breast cancer cells.
3. By blocking these signals, Hertab helps to slow down the growth of cancer cells and can even kill them.
This helps control the spread of HER2-positive breast cancer, especially in advanced stages.
References
FAQ - Lapatinib
1What is Lapatinib Tablet used for?
Lapatinib Tablet is used to treat HER2-positive breast cancer, especially when:
1. The cancer has spread to other parts of the body (advanced or metastatic stage).
2. It is used after other treatments haven’t worked well.
3. It is often given with other medicines like capecitabine or letrozole to improve results.
It works by blocking proteins (HER2 and EGFR) that help cancer cells grow.
1. The cancer has spread to other parts of the body (advanced or metastatic stage).
2. It is used after other treatments haven’t worked well.
3. It is often given with other medicines like capecitabine or letrozole to improve results.
It works by blocking proteins (HER2 and EGFR) that help cancer cells grow.
2What is the most common side effect of Lapatinib Tablet?
The most common side effect of Lapatinib Tablet is diarrhea.
This can sometimes be severe, so it's important to stay hydrated and inform your doctor if it doesn’t improve or gets worse.
Other common side effects may include:
Nausea
Vomiting
Tiredness
Rash
Loss of appetite
This can sometimes be severe, so it's important to stay hydrated and inform your doctor if it doesn’t improve or gets worse.
Other common side effects may include:
3Is it safe to take Lapatinib Tablet while drinking juice?
It is generally safe to take Lapatinib Tablet with most juices, except grapefruit juice.
Important Note:
Avoid grapefruit juice while taking Lapatinib. It can increase the level of the medicine in your blood, leading to a higher risk of side effects.
Other juices like apple, orange, or pomegranate are usually safe, but it's best to take the tablet on an empty stomach (1 hour before or 2 hours after eating or drinking anything other than water).
Always follow your doctor’s advice and read the label for any specific food or drink warnings.
Would you like a list of foods or drinks to avoid during treatment?
Important Note:
Would you like a list of foods or drinks to avoid during treatment?
4Can a pregnant woman take Lapatinib Tablet?
No, a pregnant woman should not take Lapatinib Tablet.
Lapatinib can harm the unborn baby. It is not safe during pregnancy, and women who are pregnant or planning to become pregnant should avoid using it.
Important precautions:
A pregnancy test may be needed before starting treatment.
Use effective birth control during treatment and for some time after the last dose.
If you become pregnant while taking Lapatinib, tell your doctor immediately.
Lapatinib can harm the unborn baby. It is not safe during pregnancy, and women who are pregnant or planning to become pregnant should avoid using it.
Important precautions:
5Is Lapatinib Tablet safe for breastfeeding women?
No, Lapatinib Tablet is not safe for breastfeeding women.
Lapatinib may pass into breast milk and harm the nursing baby. Because of this risk:
Breastfeeding should be stopped during treatment with Lapatinib.
Doctors usually recommend waiting for at least a few days to weeks after stopping the medicine before starting breastfeeding again (your doctor will guide you on the exact timing).
Always inform your doctor if you are breastfeeding or planning to breastfeed before starting this medicine.
Lapatinib may pass into breast milk and harm the nursing baby. Because of this risk:
6lapatinib side effects
Lapatinib is a targeted cancer therapy commonly used in combination with other drugs to treat HER2-positive breast cancer. Like all medications, it can cause side effects. Here are the common, less common, and serious side effects:
🚨 Common Side Effects
Diarrhea (most frequent and can be severe)
Nausea or vomiting
Rash
Fatigue or weakness
Loss of appetite
Hand-foot syndrome (redness, swelling, and pain on palms and soles)
⚠️ Less Common Side EffectsMouth sores
Dry skin or itching
Nail changes
Headache
Dizziness
Trouble sleeping
❗ Serious Side Effects (Seek medical help)
Severe diarrhea (can lead to dehydration)
Liver problems (elevated liver enzymes, hepatitis)
Symptoms: yellowing of skin or eyes (jaundice), dark urine, pain in the upper right side of the abdomen
Heart issues (rare but serious)
Decreased left ventricular ejection fraction (LVEF)
Symptoms: shortness of breath, swelling in legs, chest pain
Severe skin reactions (like Stevens-Johnson syndrome)
Interstitial lung disease or pneumonitis (rare)
🩺 Monitoring During Treatment
Doctors may monitor:
Liver function tests (LFTs)
Heart function (echocardiogram or MUGA scan)
Electrolyte levels (if there's significant diarrhea)
If someone experience persistent or severe symptoms, it's important to contact a healthcare provider immediately. Adjustments to dose or supportive treatments might be needed.
🚨 Common Side Effects
⚠️ Less Common Side EffectsMouth sores
❗ Serious Side Effects (Seek medical help)
🩺 Monitoring During Treatment
Doctors may monitor:
If someone experience persistent or severe symptoms, it's important to contact a healthcare provider immediately. Adjustments to dose or supportive treatments might be needed.
7lapatinib mechanism of action
Lapatinib is a dual tyrosine kinase inhibitor used primarily in the treatment of HER2-positive breast cancer. Its mechanism of action targets two key receptors involved in cancer cell growth and survival:
🔬 Mechanism of Action of Lapatinib
1. Targets Two Receptors:HER2 (Human Epidermal growth factor Receptor 2)
EGFR (Epidermal Growth Factor Receptor, also called HER1)
2. Inhibition of Tyrosine Kinase Activity:
Lapatinib binds to the intracellular (cytoplasmic) domain of these receptors.
It blocks ATP binding sites, which are needed for phosphorylation and activation of downstream signaling pathways.
🔗 Resulting Effects:
Prevents activation of signaling pathways like:
MAPK/ERK pathway (controls cell proliferation)
PI3K/AKT pathway (controls cell survival and metabolism)
Inhibits cancer cell proliferation
Induces apoptosis (programmed cell death)
Overcomes resistance seen in patients treated with trastuzumab (Herceptin)
💡 Summary
Lapatinib is a small-molecule inhibitor that blocks the tyrosine kinase domains of HER2 and EGFR, interrupting the growth signals in cancer cells and helping to control tumor progression.
Would you like a diagram illustrating this mechanism or a comparison with trastuzumab or other HER2 inhibitors like neratinib or tucatinib?
🔬 Mechanism of Action of Lapatinib
1. Targets Two Receptors:
2. Inhibition of Tyrosine Kinase Activity:
🔗 Resulting Effects:
💡 Summary
Lapatinib is a small-molecule inhibitor that blocks the tyrosine kinase domains of HER2 and EGFR, interrupting the growth signals in cancer cells and helping to control tumor progression.
Would you like a diagram illustrating this mechanism or a comparison with trastuzumab or other HER2 inhibitors like neratinib or tucatinib?
All Substitutes
Lapatinib tablet brands in India
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Lapahope 250mg tablet | 30 tablet | Glenmark Pharmaceuticals | INR 3800 |
| Lanib 250mg Tablet | 30 tablet | BDR Pharmaceuticals | INR 4500 |
| Hertab 250mg Tablet | 30 tablet | Hetero Healthcare | INR 3500 |
| Herlapsa 250mg tablet | 30 tablet | Mylan Pharmaceuticals | INR 5500 |
| Lapakast 250mg Tablet | 30 tablet | Aprazer Healthcare | INR 2700 |
| Tykerb 250mg Tablet | 30 tablet | Novartis India | INR 9000 |
| Tylidys 250mg tablet | 30 tablet | Zydus Cadila | INR 4500 |
Side Effects
Lapatinib tablet side effects
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