Jakura 5mg tablet
₹2,700.00 Original price was: ₹2,700.00.₹1,500.00Current price is: ₹1,500.00.
Indian rupee (₹) - INR
-
Indian rupee (₹) - INR
-
United States dollar ($) - USD
-
Euro (€) - EUR
Salt Composition: Tofacitinib
Manufacturer: Cipla Ltd
Packaging Size: 60 Tablets
Delivery Services
Categories: Arthritis, Rheumatoid Arthritis, Tofacitinib
Tofacitinib 5 mg
Jakura Tofacitinib 5 mg is used to treat moderate to severe conditions like rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and ulcerative colitis. It helps by reducing pain, swelling, and tenderness in the joints. This medicine also slows down damage to the bones and joints, giving better overall relief to people with these problems.
Tofacitinib 5 mg can be used alone or in combination with other medications. The tablets can be taken with or without food, and they should be taken at the same time every day. Your condition and the medications you are already taking will determine your dose. You should only use it in accordance with your doctor's instructions. If you stop taking this medication without consulting your doctor, your condition may worsen.
You may need to do blood tests before starting this medication. Do not start taking it if you have any infections. Consult with your doctor before starting the treatment if you have or have a history of tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Tofajak Tofacitinib tablets may increase susceptibility to getting infections or may worsen any current infections, so precautions, such as avoiding contact with individuals with contagious illnesses like chickenpox, measles, or flu, are advisable. Under 18-year-olds should not take this medication, and your doctor may advise against using it if you are pregnant or nursing. Regular medical examinations may be necessary under your doctor's supervision.
Tofacitinib 5 mg can be used alone or in combination with other medications. The tablets can be taken with or without food, and they should be taken at the same time every day. Your condition and the medications you are already taking will determine your dose. You should only use it in accordance with your doctor's instructions. If you stop taking this medication without consulting your doctor, your condition may worsen.
You may need to do blood tests before starting this medication. Do not start taking it if you have any infections. Consult with your doctor before starting the treatment if you have or have a history of tuberculosis, shingles, kidney or liver disease, hepatitis B or C, or blood clots in your legs or lungs. Tofajak Tofacitinib tablets may increase susceptibility to getting infections or may worsen any current infections, so precautions, such as avoiding contact with individuals with contagious illnesses like chickenpox, measles, or flu, are advisable. Under 18-year-olds should not take this medication, and your doctor may advise against using it if you are pregnant or nursing. Regular medical examinations may be necessary under your doctor's supervision.
Tofacitinib tablet uses
1. Treatment of Rheumatoid arthritis
2. Treatment of Psoriatic arthritis
3. Treatment of Ankylosing spondylitis
4. Treatment of Ulcerative colitis
5. Treatment of Alopecia
2. Treatment of Psoriatic arthritis
3. Treatment of Ankylosing spondylitis
4. Treatment of Ulcerative colitis
5. Treatment of Alopecia
Tofacitinib tablet benefits
In the Treatment of Rheumatoid Arthritis
Tofacitinib 5 mg work by stopping certain chemicals that cause inflammation. This lowers joint pain, stiffness, and swelling while also stopping bone and joint damage from getting worse. By consistently taking this medication at the same time daily, you can maximize its benefits. It is crucial to continue the treatment even if you start feeling better, as the medication not only addresses current symptoms but also serves to prevent future harm, ultimately enhancing your ability to perform daily activities and improving your overall quality of life.In the Treatment of Psoriatic Arthritis
Psoriatic arthritis emerges in individuals with psoriasis, a condition characterized by rapid skin cell growth resulting in scales and dry patches. As a variant of inflammatory arthritis, it manifests through symptoms like joint pain, stiffness, and swelling that can fluctuate over time. Tofacitinib 5 mg plays a pivotal role in alleviating the pain, stiffness, and swelling linked to this condition. Additionally, they enhance flexibility and impede disease progression, contributing significantly to the management of psoriatic arthritis and overall improvement in patients' quality of life.In the Treatment of Ankylosing Spondylitis
Ankylosing spondylitis, a less common form of arthritis, targets the spine and larger joints, typically initiating in the lower back and potentially extending to the neck or affecting joints elsewhere. Tofacitinib tablets play a vital role in diminishing pain, stiffness, and swelling in the spine and joints. By enhancing flexibility and impeding the progression of the disease, these tablets contribute to a better and more active lifestyle, offering relief to individuals dealing with ankylosing spondylitis.In the Treatment of Ulcerative Colitis
Ulcerative colitis is a condition affecting the large intestine (colon) and rectum, causing inflammation and swelling of the bowel lining. Symptoms may include bleeding, frequent diarrhea, and abdominal pain. This medication alleviates these symptoms and serves as a preventive measure against their recurrence, promoting overall well-being. It is advisable to maintain adequate hydration by consuming plenty of fluids during the course of this treatment.How to use Tofacitinib tablet
Follow your doctor's guidance regarding the dosage and duration of this medication. Swallow the tablet whole; do not chew, crush, or break it. While Tofajak tablets can be taken with or without food, it is recommended to take them at a consistent time for optimal results.
Therapeutic Effects of Tofacitinib 5 mg
Tofajak 5 mg tablet comes under the category of Janus Kinase Inhibitors and functions as a disease-modifying anti-rheumatic drug (DMARD). Janus kinase, a type of tyrosine kinase enzyme, plays a role in cytokine receptor signaling. The tablet works by inhibiting Janus kinases, disrupting the transcription of genes associated with cell growth and differentiation.
Interaction of Tofacitinib 5 mg with other drugs
Ensure you communicate with your healthcare provider regarding all the medications you are using, encompassing prescription drugs, over-the-counter medications, vaccinations, nutritional and vitamin supplements, as well as herbal products. Some medications might interact with Jakura 5mg tablets, potentially diminishing their effectiveness and giving rise to undesirable side effects.
More Information about Tofacitinib 5 mg
1. Store tofacitinib at room temperature (20°C to 25°C).
2. Keep the tablet out of the reach of children and pets.
3. If you forgot to take a dose, take it as soon as you remember.
4. However, if it is nearly time for the next dose, skip the missed dose.
5. Do not take a double dose to make up for a forgotten dose.
2. Keep the tablet out of the reach of children and pets.
3. If you forgot to take a dose, take it as soon as you remember.
4. However, if it is nearly time for the next dose, skip the missed dose.
5. Do not take a double dose to make up for a forgotten dose.
Fact Box of Tofacitinib 5 mg
1. Molecule name: Tofacitinib
2. Therapeutic class: Antirheumatoid
3. Pharmacological class: Tyrosine kinase inhibitor
4. Indications: Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, Ulcerative colitis, Polyarticular juvenile idiopathic arthritis, Juvenile psoriatic arthritis
2. Therapeutic class: Antirheumatoid
3. Pharmacological class: Tyrosine kinase inhibitor
4. Indications: Rheumatoid arthritis, Psoriatic arthritis, Ankylosing spondylitis, Ulcerative colitis, Polyarticular juvenile idiopathic arthritis, Juvenile psoriatic arthritis
References
1. HIGHLIGHTS OF PRESCRIBING INFORMATION - Tofacitinib. [revised on 2018] [cited 2023 Mar 25]. Available from:https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/203214s018lbl.pdf
2. ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS - Tofacitinib. [cited 2023 Mar 25]. Available from:chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.ema.europa.eu/en/documents/product-information/xeljanz-epar-product-information_en.pdf
3. XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [cited 2023 Mar 25]. Available from:https://www.medicines.org.uk/emc/product/2500/smpc
2. ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS - Tofacitinib. [cited 2023 Mar 25]. Available from:chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.ema.europa.eu/en/documents/product-information/xeljanz-epar-product-information_en.pdf
3. XELJANZ 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [cited 2023 Mar 25]. Available from:https://www.medicines.org.uk/emc/product/2500/smpc
FAQ - Tofacitinib
1What are the cautions of Tofacitinib tablet?
If you notice any swelling in your face, lips, tongue, throat, arms, or legs, or experience difficulty swallowing or breathing, inform your doctor promptly. The use of tofacitinib tablets may lead to a temporary reduction in white blood cell count, elevating the risk of infection.
2Does tofacitinib tablet cause high cholesterol?
Increased cholesterol levels can result from the use of tofacitinib tablets. Your doctor may check routine blood tests to monitor potential serious side effects.
3Can Tofacitinib tablet cause depression?
No, tofacitinib tablets do not cause depression. Nevertheless, individuals with autoimmune conditions often experience symptoms of depression. If you are encountering signs of depression, it is advisable to promptly consult your doctor.
4Does Tofacitinib tablet cause blood clots?
Yes, blood clots are reported in patients using tofacitinib tablets for a longer period of time. Inform your physician if you experience any symptoms of a blood clot.
5How long does it take tofacitinib tablet to work?
Tofacitinib tablets are administered as a long-term treatment. Individuals who derive benefit from this course of treatment typically observe improvement within the initial 12 weeks of starting it.
6Tofacitinib mechanism of action
Tofacitinib mechanism of action
Tofacitinib hinders intracellular signaling from the receptor to the cellular nucleus and suppresses inflammation through a unique pathway—specifically, the inhibition of Janus kinases—an avenue not accessible to biological medicines.All Substitutes
Product | Packaging Size | Manufacturer | Price |
---|---|---|---|
Jaknat 5mg tablet | 6 x 10 Tablets | Natco Pharma Ltd | INR 313 |
Tofatas 5mg tablet | 3 x 10 Tablets | Intas Pharmaceuticals | INR 300 |
Tofajak 5mg tablet | 60 Tablets | CIPLA Ltd | INR 1200 |
Side Effects
Tofacitinib tablet side effects
1. Upper respiratory tract infection
2. Headache
3. Diarrhea
4. Nasopharyngitis (inflammation of the throat and nasal passages)
You may also like…
-
Jaknat 5mg tablet
₹370.00Original price was: ₹370.00.₹313.00Current price is: ₹313.00. -
Tofajak 5mg tablet
₹1,200.00Original price was: ₹1,200.00.₹1,090.00Current price is: ₹1,090.00.