-27%
Nintib 150mg capsule
Original price was: ₹1,028.50.₹750.00Current price is: ₹750.00.
Indian rupee (₹) - INR
Salt Composition: Nintedanib
Manufacturer: CIPLA LTD
Packaging Size: 10 Capsules
Delivery Services
Nintib 150 Mg Nintedanib Soft Gelatin Capsules
Nintenib 150 mg nintedanib Soft Gelatin Capsules is used to treat idiopathic pulmonary fibrosis (a lung disease that makes it hard to breathe) and non-small cell lung cancer. It works by blocking specific processes that help these diseases grow, which helps slow down or stop the spread of cancer cells.
Take 150 mg nintedanib soft gelatin capsules with food, and try to take it at the same time every day for the best results. Your doctor will decide the right dose and how often you need to take it, based on your condition. Follow their instructions carefully—taking too much or taking it the wrong way can lead to serious side effects. It might take a few weeks or months before you notice any improvement, so don’t stop taking it unless your doctor tells you to.
Before taking 150 mg nintedanib soft gelatin capsules, discuss with your doctor if you have any bleeding issues or liver or kidney problems or if you're taking any medications for infections. This is important because many medicines can interact with nintedanib. Make sure to tell your healthcare provider about all the medicines you are currently using. This medicine is not safe to use during pregnancy or breastfeeding. To avoid pregnancy, both men and women should use reliable birth control while taking this medicine.
Take 150 mg nintedanib soft gelatin capsules with food, and try to take it at the same time every day for the best results. Your doctor will decide the right dose and how often you need to take it, based on your condition. Follow their instructions carefully—taking too much or taking it the wrong way can lead to serious side effects. It might take a few weeks or months before you notice any improvement, so don’t stop taking it unless your doctor tells you to.
Before taking 150 mg nintedanib soft gelatin capsules, discuss with your doctor if you have any bleeding issues or liver or kidney problems or if you're taking any medications for infections. This is important because many medicines can interact with nintedanib. Make sure to tell your healthcare provider about all the medicines you are currently using. This medicine is not safe to use during pregnancy or breastfeeding. To avoid pregnancy, both men and women should use reliable birth control while taking this medicine.
Nintedanib soft gelatin capsules uses
1. Treatment of idiopathic
pulmonary fibrosis
2. Pancreatic cancer
3. Small cell lung cancer
4. Liver cancer
5. Kidney cancer
6. Thyroid cancer
7. Blood cancer (chronic myeloid leukemia)
8. Gastrointestinal stromal tumor
9. Cancer of the colon and rectum
10. Non-small cell lung cancer
11. Soft tissue sarcoma
12. Chronic idiopathic myelofibrosis
13. Breast cancer
pulmonary fibrosis
2. Pancreatic cancer
3. Small cell lung cancer
4. Liver cancer
5. Kidney cancer
6. Thyroid cancer
7. Blood cancer (chronic myeloid leukemia)
8. Gastrointestinal stromal tumor
9. Cancer of the colon and rectum
10. Non-small cell lung cancer
11. Soft tissue sarcoma
12. Chronic idiopathic myelofibrosis
13. Breast cancer
Nintedanib soft gelatin capsules benefits
Treatment of Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis is a lung disease where the lung tissue becomes thick, stiff, and eventually forms scar tissue. This scarring happens due to repeated damage and healing in the lungs. The damage cannot be reversed, and common early symptoms include shortness of breath and a dry cough. 150 mg Nindanib Soft Gelatin Capsules helps by slowing down or stopping the growth of cancer cells and preventing them from spreading. Some side effects may occur while using this medicine. If you have any questions or concerns, talk to your doctor.How to use Nintedanib Soft Gelatin Capsule
Take Nintib 150 mg Nintedanib Soft Gelatin Capsules exactly as your doctor prescribes, in the right dose and for the recommended duration. Swallow the capsule whole with water—don’t chew, crush, or break it. Always take it with food for best results.
How Nintedanib Soft Gelatin Capsules works
150 mg Nintedanib Soft Gelatin Capsules is an anti-cancer medicine. It works by blocking a harmful protein that tells cancer cells to grow. It also blocks certain processes in the body that cause fibrosis, which is the thickening or scarring of tissue. By doing this, it helps slow down or stop the spread of cancer cells.
Therapeutic effects of Nintedanib soft gelatin capsules
150 mg nintedanib soft gelatin Capsules work by blocking certain enzymes called receptor tyrosine kinases (RTKs), which play a role in the development and worsening of lung fibrosis (scarring). By stopping these enzymes, the medicine helps slow down the formation of scar tissue in the lungs.
Interaction of Nintedanib soft gelatin capsules with other drugs
Make sure to tell your healthcare provider about all the medicines you are taking, including prescription drugs, over-the-counter medicines, vitamins, nutritional supplements, and herbal products. Some medications, such as P-glycoprotein (P-gp) and CYP3A4 inhibitors like ketoconazole, blood thinners (anticoagulants), St. John’s wort, and certain laxatives, can interact with 150 mg nintedanib soft gelatin capsules. These interactions may reduce how well the medicine works or increase the risk of side effects.
More Information about Nintedanib soft gelatin capsules
1. Before starting the treatment, it is recommended to perform a liver function test.
2. Store the nintedanib capsule at the room temperature of 20°C to 25°C.
3. Protect from light and moisture.
4. Keep out of reach and sight of children and pets.
2. Store the nintedanib capsule at the room temperature of 20°C to 25°C.
3. Protect from light and moisture.
4. Keep out of reach and sight of children and pets.
Fact box of Nintedanib capsules
1. Molecule name: Nintedanib
2. Therapeutic class: Antifibrotic drug
3. Pharmacological class: Tyrosine Kinase inhibitors
4. Indications:
A. Idiopathic pulmonary fibrosis.
B. Chronic fibrosing lung diseases with a progressive phenotype
C. Systemic sclerosis
2. Therapeutic class: Antifibrotic drug
3. Pharmacological class: Tyrosine Kinase inhibitors
4. Indications:
A. Idiopathic pulmonary fibrosis.
B. Chronic fibrosing lung diseases with a progressive phenotype
C. Systemic sclerosis
References
1. Boehringer Ingelheim Pharmaceuticals. Inc, [Revised on Oct 2022] [Accessed on 05th April 2023], https://content.boehringer-ingelheim.com/DAM/f0e91cee-803b-4767-8360-af1e011fc97a/ofev-us-ppi.pdf
2. Boehringer Ingelheim, Electronics Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 05th April 2023], https://www.medicines.org.uk/emc/files/pil.1786.pdf
3. Boehringer Ingelheim, U.S. Food and Drug Administration, [Revised on Mar 2020], [Accessed on 05th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/205832s013lbl.pdf
4. Lutz Wollin et al., Mode of action of Nintedanib capsule in the treatment of idiopathic pulmonary fibrosis, Eur Respir J. 2015 May; 45(5): 1434–1445. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416110/
2. Boehringer Ingelheim, Electronics Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 05th April 2023], https://www.medicines.org.uk/emc/files/pil.1786.pdf
3. Boehringer Ingelheim, U.S. Food and Drug Administration, [Revised on Mar 2020], [Accessed on 05th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/205832s013lbl.pdf
4. Lutz Wollin et al., Mode of action of Nintedanib capsule in the treatment of idiopathic pulmonary fibrosis, Eur Respir J. 2015 May; 45(5): 1434–1445. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416110/
FAQ - Nintedanib
1 How does Nintedanib 150 mg soft gelatin capsules work in the body?
Nintedanib 150 mg soft gelatin capsules work by blocking certain signals in the body that lead to lung scarring. It targets enzymes and growth factors that cause fibroblasts (special cells in the lungs) to grow and produce collagen and other proteins. These proteins are what create scar tissue. By slowing down this process, Nintedanib helps reduce the buildup of scar tissue in the lungs.
2Can Nintedanib 150 mg soft gelatib capsule cure idiopathic pulmonary fibrosis (IPF)?
Nintedanib 150 mg soft gelatin capsules do not cure idiopathic pulmonary fibrosis (IPF), but they can help slow down the disease by reducing the buildup of scar tissue in the lungs. It's important to keep taking the medicine exactly as your doctor tells you, even if you start feeling better.
3How can I manage diarrhea while taking Nintedanib 150 mg soft gelatin capsules?
If you have diarrhea while taking Nintedanib 150 mg soft gelatin capsules, it’s important to stay hydrated by drinking plenty of fluids. Your doctor may suggest over-the-counter or prescription medicines to help control it. If the diarrhea is severe or doesn’t go away, make sure to contact your doctor.
4Can Nintedanib 150 mg soft gelatin capsules cause liver damage?
Nintedanib 150 mg soft gelatin capsules can sometimes affect your liver. To keep track of your liver health, your doctor will ask you to do regular blood tests while you're taking this medicine. If you notice signs of liver problems—like yellowing of the skin or eyes (jaundice), or pain in your stomach area—contact your doctor right away.
5What dosage of Nintedanib 150 mg soft gelatin capsules should I take?
Your doctor will decide the right dose and how long you should take Nintedanib 150 mg soft gelatin capsules based on your age, weight, and medical condition. Don’t stop taking the medicine unless your doctor tells you to. If you’re considering a substitute for Nintedanib 150, talk to your doctor for suitable options. Always follow the dosage instructions given by your healthcare provider, and reach out to them if you have any questions or concerns.
6Why is liver enzyme getting elevated during treatment with Nintedanib 150 mg soft gelatin capsules?
The exact reason for the rise in liver enzymes while taking nintedanib 150 mg is not fully understood, but it's believed to be linked to how the medicine affects certain enzymes in the liver. In most cases, the increase is mild and temporary, and it usually goes away on its own or after adjusting the dose.
All Substitutes
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Nindanib 150mg capsule | 10 capsules | Glenmark Pharmaceuticals | INR 750 |
| Nintenib 150mg capsule | 10 capsules | BDR Pharmaceuticals | INR 700 |
| Nintena 150mg capsule | 10 capsules | Sun Pharmaceuticals | INR 820 |
| Cyendiv 150mg capsule | 10 capsules | Boehringer Ingelheim | INR 11960 |
Side Effects
Nintedenib capsule side effects
1. Nausea, vomiting, diarrhoea
2. Fever
3. Skin ulcer
4. Gastrointestinal perforation
5. Altered liver function values
6. Decreased appetite
7. Headache
8. Weight loss
9. Hypertension
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