Obnyx Enzalutamide 40mg capsule is a medicine used to treat prostate cancer. It works by blocking certain hormones (called androgens) that help cancer cells grow. By stopping these hormones from reaching the cancer cells, it helps slow down or stop the cancer from spreading. The dose and how long you need to take it will depend on your specific condition and how your body responds to the treatment. Important: This medicine is not safe for pregnant or breastfeeding women. Always take it exactly as your doctor tells you.
You can take Enzalutamide 40mg capsule with or without food, but try to take it at the same time every day. Always follow your doctor’s instructions for how much to take and how often—your dose may change over time based on how your body responds. Important tips:
Never take more than the prescribed dose. Taking it the wrong way or in higher amounts can lead to serious side effects.
It may take a few weeks or even months to notice the benefits, so keep taking it unless your doctor tells you to stop.
Let your doctor know if you have diabetes, seizures, or liver or kidney problems, or if you’re taking any other medicines.
Both men and women should avoid getting pregnant during treatment.
Your doctor may check your blood sugar levels regularly while you're on this medicine.
Always stay in touch with your doctor and report any unusual symptoms right away.
Enzalutamide capsule uses
Prostate cancer
Enzalutamide 40mg capsule benefits
Enzalutamide 40mg capsule offers several benefits for patients with prostate cancer, particularly in advanced or metastatic stages.
Key Benefits of Enzalutamide: 1. Inhibits Cancer Growth
Enzalutamide is an androgen receptor inhibitor.
It blocks the effect of testosterone, a hormone that fuels the growth of prostate cancer cells.
2. Effective in Hormone-Resistant Prostate Cancer
It works even in cases where cancer no longer responds to standard hormone therapy (castration-resistant prostate cancer - CRPC).
3. Delays Disease Progression
Enzalutamide slows down tumor growth, helping to extend the time before the cancer worsens.
4. Improves Overall Survival
Clinical studies show that patients taking Enzalutamide live longer compared to those on placebo or some other treatments, especially in metastatic prostate cancer.
5. Delays Need for Chemotherapy
For some patients, Enzalutamide can postpone the need for chemotherapy, improving quality of life early in the treatment course.
6. Reduces Pain and Improves Quality of Life
It can help reduce bone pain, cancer-related fatigue, and improve daily functioning.
7. Oral Administration
It's taken orally, at home — avoiding injections or hospital visits required with some other cancer therapies.
Therapeutic Effects of Obnyx Enzalutamide 40mg Capsule
Obnyx works by blocking the effects of testosterone, especially its active form called dihydrotestosterone (DHT). It does this by targeting androgen receptors—these are like “docking stations” on cells that testosterone needs to connect with in order to send growth signals. When Obnyx blocks these receptors, testosterone can't attach or send signals to the cancer cells. This stops the hormone from reaching the cell’s DNA, which slows down or stops the growth of prostate cancer cells.
Interaction of Enzalutamide Capsule with other drugs
Make sure to tell your doctor about everything you're taking—this includes prescription medicines, over-the-counter drugs, vitamins, nutritional supplements, and herbal products. Some of these may interact with Enzalutamide 40mg, which can either reduce its effectiveness or cause unwanted side effects. Always keep your healthcare provider updated to stay safe and get the best results from your treatment.
More Information about Enzalutamide Capsule
Store the Enzalutamide 40mg capsule in the original package at room temperature (20°C to 25°C).
Keep it out of reach of children and pets.
How to consume Enzalutamide Capsule
Your doctor will decide the right dose and how long you need to take the Enzalutamide 40mg capsule based on your condition and other health factors. Always follow your doctor’s instructions carefully. 1. Dosage:
The usual dose is 160 mg once daily — which means 4 capsules of 40 mg taken together at the same time each day.
2. How to take:
Take it by mouth with or without food.
Swallow the capsules whole — do not chew, open, or crush them.
3. Time of day:
Try to take it at the same time every day to maintain steady levels in your body.
4. Missed dose:
If you miss a dose and it's less than 12 hours since the usual time, take it as soon as you remember.
If it's more than 12 hours, skip the missed dose and continue with your next regular dose.
Do not double up to make up for a missed dose.
5. Things to avoid:
Avoid grapefruit juice — it can interfere with the medication.
Avoid activities that require mental alertness (like driving) if you feel drowsy or dizzy — Enzalutamide can cause fatigue and seizures in rare cases.
6. Storage:
Store at room temperature, away from moisture and heat.
Marina D. Kaymakcalan and Christy S. Harris, Prostate Cancer, Applied Therapeutics, The Clinical Use Of Drugs, 11th Edition, 2018, 2083-2100.
FAQ - Enzalutamide
1What tests are necessary before starting treatment with Enzalutamide capsule?
The recommended test before starting treatment with Enzalutamide capsules is prostate-specific antigen (PSA) testing. This blood test measures the PSA level in the blood, which may be higher in people with prostate cancer.
2What should you do if you missed a dose of Enzalutamide capsule?
If you missed the Enzalutamide capsule dose, do not overdose. If you accidentally take an extra dose, notify your healthcare provider.
3Who should not take Enzalutamide capsule?
Enzalutamide capsule is not recommended for pregnant or breastfeeding women because this drug can harm an unborn baby or pass into breast milk.
4Can you smoke while on treatment with Enzalutamide capsule?
No, it is not recommended for the patient to smoke cigarettes while on treatment because smoking can reduce the concentration of this drug in the body.
Enzalutamide works in three different ways. At the AR level, it is a powerful, competitive androgen binder. It inhibits the movement of the AR from the cytoplasm to the nucleus. It prevents AR from binding to chromosomal DNA within the nucleus, preventing tumor genes from being transcribed further.
9Enzalutamide side effects
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2. Hot flashes
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Enzalutamide is a medication that men who have benefited from specific medical and surgical procedures that lower testosterone levels can use to treat prostate cancer that has spread to other parts of the body.
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Enzalutamide works in three different ways. At the AR level, it is a powerful, competitive androgen binder. It inhibits the movement of the AR from the cytoplasm to the nucleus. It prevents AR from binding to chromosomal DNA within the nucleus, preventing tumor genes from being transcribed further.
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Enzalutamide 40mg capsule is used in the treatment of prostate cancer. This medication belongs to a class of drugs known as anti-androgens (anti-testosterone).
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28What is enzalutamide 40mg used for?
Men who have responded to medical or surgical treatments that lower testosterone levels can treat metastatic prostate cancer with enzalutamide.
29How does enzalutamide treat prostate cancer?
Enzalutamide works by interfering with testosterone's interaction with cancer cells. The FDA has approved it for the treatment of both nonmetastatic and metastatic prostate cancer, including castration-resistant prostate cancer, a condition where drugs that block testosterone production (such as leuprolide) no longer manage the cancer.
30When is the best time to take enzalutamide?
At the same time each day, swallow the tablets whole with water. You can take the tablets with or without food. If you were having hormone therapy before starting enzalutamide, you will probably continue having it together with enzalutamide, even if it's stopped working so well.
31Does enzalutamide come in tablets or capsules?
Enzalutamide comes in capsule form. The capsules come in 40 mg, 80 mg, and 160 mg dosages.
32How long do patients stay on enzalutamide?
As long as it remains effective and the side effects are manageable, you continue to take enzalutamide.
33How successful is enzalutamide?
Enzalutamide plus ADT reduced the risk of death by 34% compared to placebo plus ADT (median not reached in either group; hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P < .001). Enzalutamide plus ADT also continued to improve rPFS and other secondary endpoints.
34Can a man live 10 years with metastatic prostate cancer?
A 10-year relative survival rate of 98 percent: A decade after diagnosis, the average prostate cancer patient has only a 2 percent lower chance of survival compared to a man without prostate cancer.
35What is the longest you can live with stage 4 prostate cancer?
Stage-4 Prostate Cancer (IV)
This is the final stage of prostate cancer, characterized by a tumor that has metastasized to other parts of the body, such as the lymph nodes, lungs, liver, bones, or bladder. The 5-year survival rate for these cancers is 29%.
Enzalutamide prices and patient assistance programs Enzalutamide, a member of the antiandrogen drug class, is frequently prescribed for prostate cancer. The cost for a supply of 120 Enzalutamide 40 mg oral capsules is approximately INR 15000.
37Is enzalutamide better than chemotherapy?
In our study of men with metastatic prostate cancer who had not previously undergone chemotherapy, enzalutamide extended the time until radiographic progression or death, improved overall survival, and delayed the initiation of chemotherapy by a median of 17 months.
38Is enzalutamide a chemotherapy?
Xtandi is not a chemotherapy drug, despite its use in cancer treatment. Xtandi is a type of hormone therapy that prevents prostate cancer cells from growing and spreading by blocking the action of androgens, a group of hormones.
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Enzalutamide 40mg
Enzalutamide is a medication used to treat prostate cancer. It belongs to a class of drugs called anti-androgens (anti-testosterone), which work by blocking the effects of testosterone, thereby slowing the growth and spread of prostate cancer.
