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Piclib 125mg capsule
Original price was: ₹7,600.00.₹3,100.00Current price is: ₹3,100.00.
Indian rupee (₹) - INR
Salt Composition: Palbociclib
Manufacturer: Hetero Healthcare
Packaging Size: 21 Capsules
Delivery Services
Palbociclib 125mg capsule price in India
Piclib Palbociclib 125mg capsule is used to treat certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) that have spread to other organs. It is administered in conjunction with hormonal anti-cancer therapies.
Piclib Palbociclib 125mg capsule should be consumed with food, ideally at the same time, daily, to maximize their benefits. Your physician will determine the appropriate dosage and frequency based on your condition, which may vary over time. It's essential to adhere to your doctor's instructions precisely. Misuse or overconsumption can lead to severe side effects. Although it might take weeks or even months to see the benefits, don't stop using it unless your doctor tells you to.
Prior to taking this medication, inform your doctor if you have a history of heart disease, liver or kidney issues, or if you are currently using medications to treat infections. Informing your healthcare provider about all your medications is crucial, as this medication can interact with or influence many other drugs. Avoid using this medicine during pregnancy or while breastfeeding. We recommend effective contraception for both males and females during treatment to prevent pregnancy.
Piclib Palbociclib 125mg capsule should be consumed with food, ideally at the same time, daily, to maximize their benefits. Your physician will determine the appropriate dosage and frequency based on your condition, which may vary over time. It's essential to adhere to your doctor's instructions precisely. Misuse or overconsumption can lead to severe side effects. Although it might take weeks or even months to see the benefits, don't stop using it unless your doctor tells you to.
Prior to taking this medication, inform your doctor if you have a history of heart disease, liver or kidney issues, or if you are currently using medications to treat infections. Informing your healthcare provider about all your medications is crucial, as this medication can interact with or influence many other drugs. Avoid using this medicine during pregnancy or while breastfeeding. We recommend effective contraception for both males and females during treatment to prevent pregnancy.
Palbociclib uses
. Breast cancer
Palbociclib benefits
Breast Cancer
Piclib 125mg capsule is effective in treating breast cancer and can be utilized alone or in conjunction with other medications or treatment methods, such as chemotherapy. It alleviates breast cancer symptoms such as breast lumps, bloody discharge from nipples, or alterations in breast shape or texture. Piclib capsules halt cancer cell growth and inhibit multiplication. If any side effects are troublesome, consult your doctor for guidance.How Palbociclib works
Piclib 125mg capsule is an anti-cancer medication that operates by targeting cyclin-dependent kinases 4 and 6, which are chemical messengers downstream of signaling pathways that drive cell proliferation. By inhibiting cyclin-dependent kinases 4 and 6, this medicine halts the cancer cell cycle, effectively impeding cell growth. Additionally, it specifically targets estrogen receptor-positive breast cancer cells by disrupting the cell cycle.
How to use Palbociclib 125mg capsule
Follow your doctor's instructions regarding the dosage and duration of
Piclib Palbociclib capsules. It should be taken with food.
Therapeutic Effects of Palcociclib 125mg Capsule
Piclib Palbociclib 125mg capsule functions by inhibiting the activity of cyclin-dependent kinases 4 and 6, essential for cell division and growth. This action slows cell growth and impedes the spread of cancer cells.
Interaction of Palbociclib 125mg capsule with other drugs
Before starting treatment, discuss with your doctor all your medications, whether prescribed, over-the-counter, nutritional, or vitamin supplements, as well as any herbal products you have previously taken. It's essential to note that concurrent use of
Piclib Palbociclib 125mg capsule with CYP3A4 inhibitors like fentanyl has been associated with increased fentanyl toxicity. Some medications may interact with the drug's efficacy.
More Information about Palbociclib 125mg Capsule
1. Keep the Piclib (Palbociclib) 125mg capsule out of sight and reach of children.
2. Store at 20°C to 25°C.
2. Store at 20°C to 25°C.
Fact Box of Piclib (Palbociclib) 125mg capsule
1. Molecule name: Palbociclib
2. Therapeutic class: Cyclin-dependent kinase inhibitor
3. Pharmacological class: Anti-Neoplastics
4. Indications: HR-positive, HER2-negative advanced or metastatic breast cancer
2. Therapeutic class: Cyclin-dependent kinase inhibitor
3. Pharmacological class: Anti-Neoplastics
4. Indications: HR-positive, HER2-negative advanced or metastatic breast cancer
References
1. Pfizer Labs, US Food and Drug Administration, [Revised on March 2017] [ Accessed on 26 Nov 2022],https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207103s004lbl.pdf
2. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022],https://www.medicines.org.uk/emc/files/pil.4449.pdf
3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022;https://pubmed.ncbi.nlm.nih.gov/26324355/
4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022;https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
2. Pfizer Limited, Electronic medicines compendium (emc), [Revised on June 2021] [ Accessed on 26 Nov 2022],https://www.medicines.org.uk/emc/files/pil.4449.pdf
3. Neha S Mangini et al; Palbociclib: A Novel Cyclin-Dependent Kinase Inhibitor for Hormone Receptor-Positive Advanced Breast Cancer; The Annals of Pharmacotherapy; Published on Nov 2015; Accessed on 26/11/2022;https://pubmed.ncbi.nlm.nih.gov/26324355/
4. Palbace; Pfizer; Revised on Oct 2021; Accessed on 26/11/2022;https://labeling.pfizer.com/ShowLabeling.aspx?id=14029
FAQ - Palbociclib
1Is Palbociclib (Piclib) 125mg capsule a form of targeted therapy?
Yes, Palbociclib (Piclib) 125mg capsule is categorized as targeted therapy and is classified as a cyclin-dependent kinase inhibitor.
2Is hair loss a common side effect of the Palbociclib (Piclib) 125mg capsule?
Certainly, hair loss or thinning is a potential side effect of taking Palbociclib (Piclib) 125mg capsule may cause hair loss or thinning. If you experience any side effects, including this one, consult your doctor for guidance.
3Is Palbociclib (Piclib) 125mg capsule suitable for use in children?
Piclib 125 mg capsule is not recommended for adolescents or children under 18 years old.
4Can Palbociclib (Piclib) 125mg capsule impact fertility?
Yes, Palbociclib (Piclib) 125mg capsule may potentially diminish fertility in men, impacting their ability to father children. Therefore, it is advisable for men to contemplate sperm preservation prior to initiating this medication.
5Can Palbociclib (Piclib) 125mg capsule affect blood cell count?
Rewriting this Palbociclib (Piclib) 125mg capsule may decrease the count of white blood cells, potentially weakening the immune system and increasing susceptibility to infections. Regular blood tests are recommended during the Palbociclib (Piclib) 125mg capsule treatment.
6Palbociclib
Palbociclib
Palbociclib is prescribed alongside another medication as an initial therapy for a specific type of hormone receptor-positive, advanced breast cancer that has metastasized. Additionally, it is used with fulvestrant (Faslodex) to treat hormone receptor-positive, advanced breast cancer in individuals who have previously responded to antiestrogen treatment like tamoxifen (Soltamox). Palbociclib, a kinase inhibitor, works by inhibiting the abnormal protein activity that causes cancer cells to proliferate, thereby impeding or slowing cancer cell spread.7abemaciclib palbociclib ribociclib
abemaciclib palbociclib ribociclib
When compared to palbociclib, ribociclib exhibited notably higher gastrointestinal (GI) toxicity, including an increased incidence of grade 1–2 nausea, grade 1–2 vomiting, grade 3–4 vomiting, and grade 3–4 transaminitis. Conversely, abemaciclib demonstrated significantly more diarrhea of any grade and a higher incidence of grade 3–4 anemia compared to ribociclib.8palbociclib brand name
palbociclib brand name
1. Piclib2. Ciclib 125mg
3. Bdpalbo 125mg
4. Palnat 125mg
5. Pabreca 125mg
6. Kixta 125mg
9palbociclib package insert
palbociclib package insert
palbociclib package insert film coated capsule10palbociclib side effects
palbociclib side effects
1. Tiredness2. Hair loss
3. Dry skin, rash
4. Infections
5. Low blood cell counts
6. Decreased of appetite
7. Nausea, vomiting
8. Diarrhea
9. Swelling of lips and mouth
10. Changes in taste
11. Nose bleed
12. Dry eye, blurred vision, increased
13. tearing
11palbociclib mechanism of action
palbociclib mechanism of action
In cancer cells that have a functional retinoblastoma tumor suppressor gene (RB), palbociclib stops cell growth and DNA replication because of how it works.12palbociclib cost
palbociclib cost
Palbociclib cost: INR 310013 palbociclib prescribing information
palbociclib prescribing information
Follow your doctor's instructions regarding the dosage and duration of Palbociclib (Piclib) capsules. It should be taken with food.14palbociclib price
palbociclib price
: INR 310015side effects of palbociclib
side effects of palbociclib
1. Tiredness2. Hair loss
3. Dry skin, rash
4. Infections
5. Low blood cell counts
6. Decreased of appetite
7. Nausea, vomiting
8. Diarrhea
9. Swelling of lips and mouth
10. Changes in taste
11. Nose bleed
12. Dry eye, blurred vision, increased tearing
16palbociclib 125mg price in India
palbociclib 125mg price in India
: INR 310017Piclib 125mg price in India
Piclib 125mg price in India
: INR 310018palbociclib 125 mg price
palbociclib 125 mg price
: INR 310019palbociclib 125 mg price in india
palbociclib 125 mg price in india
: INR 310020palbociclib 125mg price
palbociclib 125mg price
: INR 310021piclib 125mg price
piclib 125mg price: INR 3100
22piclib 125 mg price
piclib 125 mg price: INR 3100
23piclib 125 mg price in india
piclib 125 mg price in india: INR 3100
24piclib 125mg price in india
piclib 125mg price in india: INR 3100
25palbociclib price in india
palbociclib price in india: INR 3100
26palbociclib 125mg capsule
palbociclib 125mg capsule
Palbociclib is a type of medication known as a kinase inhibitor. It functions by blocking the abnormal protein that signals cancer cells to multiply, helping to slow down or stop their spread.All Substitutes
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Ciclib 125mg capsule | 21 capsule | Shilpa Medicare | INR 2700 |
| Bdpalbo 125mg capsule | 21 capsule | BDR Pharmaceuticals | INR 3200 |
| Palnat 125mg capsule | 21 capsule | Natco Pharma | INR 3650 |
| Pabreca 125mg capsule | 21 capsule | Lupin Ltd | INR 5600 |
| Kixta 125mg capsule | 21 capsule | Zydus Cadila | INR 5900 |
| Piciclib 125mg capsule | 21 capsule | Cipla Ltd | INR 4050 |
Side Effects
Palbociclib side effects
1. Tiredness
2. Hair loss
3. Dry skin, rash
4. Infections
5. Low blood cell counts
6. Decreased of appetite
7. Nausea, vomiting
8. Diarrhea
9. Swelling of lips and mouth
10. Changes in taste
11. Nose bleed
12. Dry eye, blurred vision, increased tearing
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