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Everolimus 10 mg Tablet (Afinitor)
Original price was: $208.70.$195.00Current price is: $195.00.
United States dollar
Salt Composition: Everolimus
Manufacturer: Novartis India
Packaging Size: 10 Tablet
Delivery Services
Everolimus 10 mg tablet (Afinitor) – Overview & Benefits
Everolimus 10 mg tablet (Afinitor) helps prevent the body from rejecting a transplanted organ by controlling the immune system so it can accept the new organ. It is also used along with other medicines to treat cancers of the breast, pancreas, lungs, and kidneys.
Take everolimus 10mg tablets exactly as your doctor prescribes, in the correct dose and for the right duration. You can take it with or without food, but try to take it at the same time each day. Do not take more than the recommended dose, as an overdose can cause serious side effects.
Before starting this medicine, talk to your doctor if you're taking any other medications or have any existing health conditions. If you are pregnant or breastfeeding, let your doctor know before beginning treatment. During the course of treatment, your doctor may ask for some lab tests to check how the medicine is affecting your body. This medicine may impact fertility in both men and women, so speak to your doctor if you are planning to have a child.
Take everolimus 10mg tablets exactly as your doctor prescribes, in the correct dose and for the right duration. You can take it with or without food, but try to take it at the same time each day. Do not take more than the recommended dose, as an overdose can cause serious side effects.
Before starting this medicine, talk to your doctor if you're taking any other medications or have any existing health conditions. If you are pregnant or breastfeeding, let your doctor know before beginning treatment. During the course of treatment, your doctor may ask for some lab tests to check how the medicine is affecting your body. This medicine may impact fertility in both men and women, so speak to your doctor if you are planning to have a child.
Uses of Everolimus 10 mg tablet
1. Organ Transplant:
Prevents rejection of kidney or liver transplants by suppressing the immune system.
2. Cancer Treatment:
Breast Cancer: Used for advanced hormone receptor-positive, HER2-negative breast cancer.
Kidney Cancer: Treats advanced renal cell carcinoma when other treatments fail.
Pancreatic Neuroendocrine Tumors: Helps control tumor growth in the pancreas.
Lung Neuroendocrine Tumors: Used for treating certain slow-growing lung tumors.
Brain Tumors: Manages subependymal giant cell astrocytoma (SEGA), especially in patients with tuberous sclerosis complex (TSC).
Renal Angiomyolipoma: Treats non-cancerous kidney tumors associated with TSC.
Benefits of Everolimus 10 mg Tablet
How Everolimus 10 mg tablet works
Everolimus 10mg tablet works by targeting and blocking a protein called mTOR (mammalian target of rapamycin). Here's how it functions:
1. Immune System Regulation (for organ transplant patients):mTOR is involved in the immune system’s response. By inhibiting mTOR, Everolimus reduces the activity of the immune system, preventing it from rejecting a transplanted organ (like a kidney or liver).
2. Cancer Treatment:
mTOR helps cancer cells grow and divide. By blocking this protein, Everolimus slows down or stops the growth of cancer cells, especially in tumors of the breast, pancreas, kidneys, lungs, and brain.
In simple terms, Everolimus helps prevent organ rejection by calming the immune system and fights cancer by slowing down the growth of abnormal cells.
1. Immune System Regulation (for organ transplant patients):
How to use Everolimus 10 mg tablet
1. Follow Your Doctor's Instructions:
Always take Everolimus exactly as your doctor prescribes. The dosage and duration will depend on your specific condition.
2. When to Take:
Take the tablet at the same time each day to help you remember.
You can take it with or without food.
3. Swallow the Tablet Whole:
Do not crush, chew, or break the tablet. Swallow it whole with a glass of water.
4. Avoid Overdose:
Do not take more than the prescribed dose. An overdose may cause serious side effects.
If you miss a dose, take it as soon as you remember, unless it's almost time for the next dose. Do not take two doses at once.
5. Regular Check-ups:
Your doctor may recommend regular blood tests to check how the medicine is affecting your body.
6. Other Instructions:
If you’re pregnant, breastfeeding, or planning to have a child, consult your doctor before using Everolimus.
Always take Everolimus exactly as your doctor prescribes. The dosage and duration will depend on your specific condition.
2. When to Take:
Therapeutic Effects of Afinitor Everolimus 10 mg tablet
Afinitor 10mg tablet works by blocking a protein called mTOR (mammalian target of rapamycin), which controls cell growth. By inhibiting mTOR, everolimus slows the growth of abnormal cancer cells, reduces tumor size, and can improve outcomes in patients with certain cancers.
Interaction of Everolimus 10 mg tablte with other drugs
Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medicines, vitamin or nutritional supplements, and herbal products. Some medications may interact with the Everolimus 10mg tablet, potentially reducing its effectiveness or causing unwanted side effects.
How to store Everolimus Tablet
References
FAQ - Everolimus
1What you should know before taking Everolimus 10 mg tablet?
1. Inform Your Doctor About Your Health Conditions:
Tell your doctor if you have any liver or kidney problems, infection, or a history of lung or breathing issues.
If you have any allergies to Everolimus or other medicines, inform your doctor.
2. Medications You Are Taking:
Make sure to inform your doctor about all the medicines you’re taking, including prescription medications, over-the-counter drugs, vitamin or nutritional supplements, and herbal products. Some medications can interact with Everolimus and affect its effectiveness or cause side effects.
3. Pregnancy and Breastfeeding:
Everolimus can harm an unborn baby, so if you are pregnant or planning to become pregnant, talk to your doctor before using this medication.
If you are breastfeeding, inform your doctor, as Everolimus can pass into breast milk.
4. Fertility Concerns:
Everolimus may affect fertility in both men and women. If you are planning to have a child, consult your doctor beforehand.
5. Infection Risk:
Everolimus can weaken the immune system, increasing the risk of infections. Make sure to avoid contact with people who have infections, and report any symptoms of infection to your doctor.
6. Lab Tests and Monitoring:
Your doctor may recommend regular blood tests to monitor the effects of Everolimus on your body, including liver and kidney function.
7. Avoid Grapefruit:
Grapefruit and grapefruit juice may interact with Everolimus, so it's best to avoid them unless your doctor advises otherwise.
Make sure to follow your doctor’s instructions closely and discuss any concerns you have before starting treatment with Everolimus.
2Is it safe to use Everolimus tablet during pregnancy?
No, Everolimus is not considered safe to use during pregnancy.
Risk to the unborn baby: Everolimus may cause harm to a developing fetus and can increase the risk of birth defects or pregnancy complications.
Animal studies: Research in animals has shown negative effects on the fetus, and although human data is limited, the potential risks are significant.
Birth control recommended: Women of childbearing age should use effective contraception during treatment and for at least 8 weeks after the last dose of Everolimus.
If you are pregnant, planning to become pregnant, or think you might be pregnant, talk to your doctor immediately before taking this medicine.
3What are the side effects of Everolimus Tablet?
Common Side Effects of Everolimus Tablet:
Mouth ulcers or sores
Weakness or tiredness (fatigue)
Nausea or vomiting
Diarrhea
Loss of appetite
Cough or shortness of breath
Skin rash or itching
Increased risk of infections (due to weakened immune system)
Headache
Swelling in hands, feet, or ankles
High blood sugar (hyperglycemia)
Menstrual irregularities in women
Serious Side Effects (call your doctor immediately if you notice these):
Persistent fever, chills, or signs of infection
Difficulty breathing or chest pain
Severe mouth or throat pain
Unusual bleeding or bruising
Signs of allergic reaction: swelling, severe rash, itching, or trouble breathing
Because Everolimus affects the immune system and other body functions, regular monitoring through lab tests is usually needed during treatment.
4Is it safe to undergo surgery while on treatment with Everolimus tablet?
Caution is needed when undergoing surgery while taking Everolimus.
1. Delayed Wound Healing:Everolimus can slow down the body's ability to heal wounds, including surgical cuts, which increases the risk of infection and complications after surgery.
2. Higher Risk of Infection:
Because it weakens the immune system, Everolimus may raise the chance of infections during and after surgery.
3. What You Should Do:
Inform your surgeon and doctor well in advance if you're scheduled for any surgery.
Your doctor may decide to pause Everolimus before and after surgery to allow proper healing.
Never stop or change your medication without medical advice.
In summary: Everolimus can affect surgical outcomes, so always discuss planned procedures with your healthcare team.
1. Delayed Wound Healing:
5 Can I drink alcohol while taking Everolimus tablet?
It is generally advised to limit or avoid alcohol while taking Everolimus.
1. Liver strain:Both alcohol and Everolimus can affect liver function. Using them together may increase the risk of liver damage.
2. Weakened immune system:
Everolimus already lowers your immunity. Alcohol can further weaken your body’s defenses, raising the risk of infections.
3. Side effects may worsen:
Alcohol may increase side effects like fatigue, nausea, or dizziness when combined with Everolimus.
4. Interference with treatment:
Alcohol could potentially interfere with how well the medicine works, especially during cancer treatment or after an organ transplant.
Recommendation:
Talk to your doctor before consuming alcohol while on Everolimus. If allowed, it should be in moderation and only under medical advice.
1. Liver strain:
6What is Everolimus 10mg tablet used for?
Everolimus 10mg tablet is used to treat various types of cancers, including kidney, breast, and pancreatic neuroendocrine tumors. It’s also used for certain non-cancerous tumors in patients with tuberous sclerosis complex (TSC).
7What are the side effects of Everolimus 10mg?
Common side effects include mouth ulcers, fatigue, rash, infections, and low blood counts. Always consult your doctor if any severe or persistent side effects occur.
8How should Everolimus 10mg tablet be taken?
Everolimus should be taken once daily at the same time, with or without food. Swallow the tablet whole with water and follow your doctor’s instructions closely.
9Is Everolimus 10mg used for kidney cancer?
Yes, Everolimus 10mg is approved for the treatment of advanced kidney cancer (renal cell carcinoma), especially when other treatments have not worked.
10Can I buy Everolimus 10mg tablet online?
Yes, you can purchase Everolimus 10mg tablets online from licensed pharmacies or international suppliers. Always ensure you have a valid prescription before ordering.
11What is Everolimus 10mg tablet used for?
Everolimus 10mg tablet is used to prevent organ rejection in transplant patients by regulating the immune system. It is also prescribed in combination with other medicines to treat cancers of the breast, pancreas, lungs, and kidney.
12How should Everolimus 10mg tablet be taken?
It must be taken exactly as prescribed by your doctor, in the correct dose and duration. Everolimus can be taken with or without food, but it should be taken at the same time every day to maintain consistent blood levels.
13What are the common side effects of Everolimus 10mg tablet?
The most common side effects include infection, fever, cough, fatigue, diarrhea, mouth sores, rash, decreased appetite, and upper respiratory infections. Patients should report severe or persistent side effects to their doctor.
14Can Everolimus 10mg tablet be exported from India?
Yes, Everolimus 10mg tablets are available for bulk export from India. GMP‑certified suppliers provide worldwide shipping with proper documentation, including HS code compliance and customs clearance.
15What precautions should be taken while using Everolimus 10mg tablet?
Patients should inform their doctor about any existing infections, liver problems, or medications they are taking. Regular monitoring of blood counts and liver function is recommended during treatment.
16What is the price of Everolimus 10mg tablet in India?
Prices vary depending on the brand. For example, Evelimus 10mg (Emcure) and Rolimus 10mg (Cipla) are commonly available, with prices ranging between INR 6850 per strip depending on manufacturer and packaging.
All Substitutes
Everolimus tablet brands in India
| Product | Packaging Size | Manufacturer | Price |
|---|---|---|---|
| Torinat 10mg tablet | 10 tablet | Natco Pharma | INR 3400 |
| Everbliss 10mg Tablet | 10 tablet | BDR Pharmaceuticals | INR 6850 |
| Rolimus 10mg Tablet | 10 tablet | CIPLA Ltd | INR 8000 |
| Evermil 10mg Tablet | 10 tablet | Glenmark Pharmaceuticals | INR 5500 |
Side Effects
Everolimus tablet side effects
- Infection (chills, increased temperature)
- Coughing
- Wheezing
- Excessive thirst
- High urine output or severely decreased urine output
- Tiredness
- Bleeding
- Increased appetite with weight loss
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